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Merck

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Synonimy:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Gatunek:
Human CYP19A1 (1588), Mouse Cyp19a1 (13075), Rat Cyp19a1 (25147), Goat CYP19A1 (100861413), Horse CYP19A1 (100009712), dog CYP19A1 (494003), chicken CYP19A1 (414854), Domestic Rabbit CYP19A1 (100328545), cow CYP19A1 (281740)
Identyfikator UniProtKB:
P11511, Q16731, Q3B764, Q58FA0
Identyfikator genu:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4500606
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB5702040
Przeciwciało przeciw aromatazie (CYP19A1), klon 5C5N7, królicze monoklonalne, ,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
SAB1410280
Anti-CYP19A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
ZRB2945
Anti-Aromatase Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey
Zastosowanie
affinity binding assay
immunohistochemistry
western blot
HPA051194
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Cell Lines

Numer produktu
Opis
Gatunek
MTOXCE19A1
CypExpress™ Aromatase, ,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
L6545
Letrozole, ≥98% (HPLC),
Gatunek
human
PHR1540
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
1356971
Letrozole, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Y0000685
Letrozole, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
BP1234
Letrozole, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
A9657
DL-Aminoglutethimide, ,
Gatunek
human, rat

esiRNA

Numer produktu
Opis
Gatunek
EHU036781
MISSION® esiRNA, targeting human CYP19A1,
Gatunek
human
EMU044241
MISSION® esiRNA, targeting mouse Cyp19a1,
Gatunek
mouse