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Merck

CACNA2D2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

Synonimy:
CACNA2D, LUAC11.1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(9254) Summary: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(56808) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • Rat(300992) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • sheep(101115165) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • domestic cat(101095887) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • cow(785909) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • chicken(430150) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • Zebrafish(541376) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • dog(100688870) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • naked mole-rat(101710707) calcium channel, voltage-dependent, alpha 2/delta subunit 2
  • domestic guinea pig(100734097) calcium channel, voltage-dependent, alpha 2/delta subunit 2

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CACNA2D2 antibody produced in mouse, clone 3A4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-CACNA2D2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Bepridil hydrochloride, powder,
Gatunek
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CACNA2D2,
Gatunek
human