Przejdź do zawartości
Merck

CACNA1D

calcium channel, voltage-dependent, L type, alpha 1D subunit

Synonimy:
CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, SANDD
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(776) Summary: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
  • Mouse(12289) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Rat(29716) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • sheep(101106371) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic cat(101088394) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Domestic Rabbit(100327259) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • chicken(395895) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Horse(100051186) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • dog(484724) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic guinea pig(100726255) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • cow(408013) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • naked mole-rat(101714832) calcium channel, voltage-dependent, L type, alpha 1D subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Felodipine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Felodipine, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Felodipine, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Nimodipine, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Nimodipine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CACNA1D antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoclonal Anti-CACNA1D antibody produced in mouse, clone S48A-9, 1 mg/mL, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Margatoxin, ,
Gatunek
mouse, rat, human
Amlodipine besylate, ≥98% (HPLC),
Gatunek
human
Amlodipine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Nifedipine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CACNA1D,
Gatunek
human