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Merck

ABCC1

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Synonimy:
ABC29, ABCC, GS-X, MRP, MRP1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4363) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
  • Mouse(17250) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Rat(24565) ATP-binding cassette, subfamily C (CFTR/MRP), member 1
  • naked mole-rat(101725452) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • sheep(101110991) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic cat(101101279) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Horse(791240) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • chicken(395416) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Domestic Rabbit(100345841) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Zebrafish(100002010) ATP-binding cassette, sub-family C, member 1
  • cow(281588) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic guinea pig(100734674) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • dog(403453) ATP-binding cassette, sub-family C (CFTR/MRP), member 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ABCC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Przeciwciało przeciwko białku związanemu z opornością wielolekową, klon MRPm6, culture supernatant, clone MRPm6, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry

western blot
Przeciwciało anty-MRP1, klon QCRL-1, clone QCRL-1, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Przeciwciało anty-MRP1, klon MRPm5, clone MRPm5, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry

western blot
Przeciwciało anty-MRP1/ABCC1, klon 0J6M2, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot

Cell Lines

Numer produktu
Opis
Gatunek
MRP1 Knockout komórki Caco-2, one vial,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Chloroquine diphosphate salt, powder or crystals, 98.5-101.0% (EP),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Abcc1,
Gatunek
mouse
MISSION® esiRNA, targeting human ABCC1,
Gatunek
human