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PARP1

poly (ADP-ribose) polymerase 1

Synonimy:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PARP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
microarray

western blot
Anti-Poly ADP-ribose Antibody, clone 10H, clone 10H, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
western blot
Anti-PARP-1 Antibody, clone 12N17 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Rabbit anti-PARP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Benzamide, 99%,
Gatunek
human
Benzamide, purified by sublimation, ≥99.5%,
Gatunek
human
6-(5H)-Phenanthridinone, technical grade,
Gatunek
human
3-Aminobenzamide, ≥99% (TLC),
Gatunek
mouse
Nicotinamide, ≥99.5% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
PARP-1 human, recombinant, expressed in E. coli,
Gatunek
human
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Gatunek
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Gatunek
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Parp1,
Gatunek
mouse
MISSION® esiRNA, targeting human PARP1,
Gatunek
human