T2379

筒箭毒碱 盐酸盐 五水合物

≥97%

• 别名: (+)-Tubocurarine hydrochloride
• 经验公式（希尔记法）: C₃₇H₄₁ClN₂O₆ · HCl · 5H₂O
• CAS号: 6989-98-6
• 分子量: 771.72
• MDL號碼: MFCD00150157
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24900034
• NACRES: NA.77

属性

• 品質等級: 200
• 化驗: ≥97%
• 溶解度: H₂O: soluble 50 mg/ml, with heating as required, clear to slightly hazy, colorless to yellow; ethanol: soluble; methanol: soluble
• 儲存溫度: 2-8°C
• SMILES 字串: O.O.O.O.O.Cl.[Cl-].COc1cc2CCN(C)[C@H]3Cc4ccc(Oc5c(O)c(OC)cc6CC[N+](C)(C)[C@H](Cc7ccc(O)c(Oc1cc23)c7)c56)cc4
• InChI: 1S/C37H40N2O6.2ClH.5H2O/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33;;;;;;;/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41);2*1H;5*1H2/t28-,29+;;;;;;;/m0......./s1
• InChI 密鑰: WMIZITXEJNQAQK-GGDSLZADSA-N
• 基因資訊: human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

说明

應用

Tubocurarine hydrochloride pentahydrate has been used as a acetylcholinesterase inhibitor (Ach) inhibitor in myotubes, muscle and as neuromuscular junction blocker in zebra fish embryos.

生化／生理作用

Tubocurarine is a muscle relaxant and a nicotinic acetylcholine receptor antagonist. It can induce neuromuscular blocking.

特點和優勢

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

準備報告

Tubocurarine hydrochloride pentahydrate is soluble in water at 50 mg/ml (with heat as required) and yields a clear to slightly hazy, colorless to yellow solution. It is also soluble in methanol and ethanol.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 + P330 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges