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品質等級
化驗
≥98% (HPLC)
形狀
solid
溶解度
DMSO: soluble 19 mg/mL
SMILES 字串
COC(=O)c1ccccc1NC(=O)c2ccc(F)cc2
InChI
1S/C15H12FNO3/c1-20-15(19)12-4-2-3-5-13(12)17-14(18)10-6-8-11(16)9-7-10/h2-9H,1H3,(H,17,18)
InChI 密鑰
KIAPWMKFHIKQOZ-UHFFFAOYSA-N
應用
Exo 1 已被用作 BRB80 缓冲液的组成成分,以被用于研究外壳蛋白 1 (COPI) 介导的膜运输。它也被用作高尔基体抑制剂来研究其对长散布的核元件 1 (L1) 逆转录转座的影响。
生化/生理作用
Exo 1 是一种可渗透细胞的邻氨基苯甲酸甲酯类似物,可促进二磷酸腺苷 (ADP)-核糖基化因子 (ARF) 1 从高尔基体膜释放。它还可抑制内质网 (ER) 和高尔基体之间的膜运输。
可逆的胞吐抑制剂; 高尔基体ARF 1(ADP-核糖基化因子)GTPase激活剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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