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Merck

95098

Sigma-Aldrich

(E)-1-羟基-2-甲基-2-丁烯基4-焦磷酸酯 锂盐

≥95.0% (TLC)

别名:

(E)-4-羟基-3-甲基-2-烯基二磷酸酯 锂盐, 1-羟基-2-甲基-2-(E)-丁烯基-4-二磷酸酯, HDMAPP, HMBPP, HO-DMAPP

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About This Item

经验公式(希尔记法):
C5H12O8P2 · xLi+
分子量:
262.09 (free acid basis)
分類程式碼代碼:
12352302
NACRES:
NA.85

品質等級

化驗

≥95.0% (TLC)

形狀

solid

儲存溫度

−20°C

InChI

1S/C5H12O8P2/c1-5(4-6)2-3-12-15(10,11)13-14(7,8)9/h2,6H,3-4H2,1H3,(H,10,11)(H2,7,8,9)/p-3

InChI 密鑰

MDSIZRKJVDMQOQ-UHFFFAOYSA-K

生化/生理作用

HMB-PP是类异戊二烯生物合成的非甲羟戊酸途径(MEP途径)的一种中间体;它被证明是一种有效的γδT细胞激活剂

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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FEBS letters, 544(1-3), 4-10 (2003-06-05)
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The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants.
M Rohmer
Natural product reports, 16(5), 565-574 (1999-12-10)
M Hintz et al.
FEBS letters, 509(2), 317-322 (2001-12-14)
The gcpE and lytB gene products control the terminal steps of isoprenoid biosynthesis via the 2-C-methyl-D-erythritol 4-phosphate pathway in Escherichia coli. In lytB-deficient mutants, a highly immunogenic compound accumulates significantly, compared to wild-type E. coli, but is apparently absent in
Felix Rohdich et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(3), 1158-1163 (2002-01-31)
Isopentenyl diphosphate and dimethylallyl diphosphate serve as the universal precursors for the biosynthesis of terpenes. Although their biosynthesis by means of mevalonate has been studied in detail, a second biosynthetic pathway for their formation by means of 1-deoxy-D-xylulose 5-phosphate has

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