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G6025

Sigma-Aldrich

香叶基香叶基焦磷酸盐 铵盐

solution, ≥95% (TLC), ~1 mg/mL in methanol: NH4OH (7:3)

别名:

GGPP, 全反式-3,7,11,15-四甲基-2,6,10,14-十六烷基焦磷酸酯 铵盐

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About This Item

经验公式（希尔记法）:
C20H36O7P2 · xNH3
CAS号:
6699-20-3
分子量:
450.44 (free acid basis)
MDL號碼:
MFCD00156114
分類程式碼代碼:
12352211
PubChem物質ID:
24895243
NACRES:
NA.77

化驗

≥95% (TLC)

形狀

solution

包裝

vial of 200 μg

濃度

~1 mg/mL in methanol: NH4OH (7:3)

儲存溫度

−20°C

SMILES 字串

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O

InChI

1S/C20H36O7P2/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-26-29(24,25)27-28(21,22)23/h9,11,13,15H,6-8,10,12,14,16H2,1-5H3,(H,24,25)(H2,21,22,23)/b18-11+,19-13+,20-15+

InChI 密鑰

OINNEUNVOZHBOX-QIRCYJPOSA-N

相关类别

應用

香叶基香叶基焦磷酸盐已用于：
  • 制备用于Rab GGTase测定的2.5X反应缓冲液
  • 添加到培养物中，进一步驱动Hmg2降解
  • 用作体外酶促测定鉴定异戊二烯基转移酶时的底物
  • 逆转洛伐他汀作用，还用于检验GGPP在研究中的潜在作用，以评估在体外共培养血管生成模型中，洛伐他汀对黑素瘤细胞系的作用

生化／生理作用

来自细胞内甲羟戊酸途径的类异戊二烯可用于几种低分子量G蛋白（包括Ras）的异戊烯化。 萜烯生物合成中间体。
香叶基香叶基焦磷酸酶（GGPP）是一种主要的酶，参与叶绿体的次级代谢。GGPP合酶在类萜生物合成中起关键作用。香叶基香叶基焦磷酸酶介导的蛋白质香叶基香叶基化参与心室的发育。它还可充当特定阶段的信号，调节妊娠中期心脏细胞结构的形成。

特點和優勢

该化合物是环核苷酸研究的推荐产品。点击此处，了解更多精选环核苷酸产品。了解更多有关用于其他研究领域的生物活性小分子的信息，请访问 sigma.com/discover-bsm。

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

51.8 °F - closed cup

閃點（°C）

11 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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