496189

氯仿

biotech. grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• 别名: 三氯甲烷
• 经验公式（希尔记法）: CHCl₃
• CAS号: 67-66-3
• 分子量: 119.38
• Beilstein: 1731042
• MDL编号: MFCD00000826
• UNSPSC代码: 12191502
• PubChem化学物质编号: 329757487
• NACRES: NA.04
• 等级: biotech. grade
• 方案: ≥99.8%
• 沸点: 60.5-61.5 °C (lit.)
• 蒸汽压: 160 mmHg ( 20 °C)

属性

• 等级: biotech. grade
• 质量水平: 100
• 蒸汽密度: 4.1 (vs air)
• 蒸汽压: 160 mmHg ( 20 °C)
• 方案: ≥99.8%
• 表单: liquid
• 包含: 0.5-1.0% ethanol as stabilizer
• 杂质: <0.01% water
• 蒸发残留物: <0.0003%
• 颜色: APHA: ≤10
• 折射率: n20/D 1.445 (lit.)
• pH值（酸碱度）: 5.2-6.4
• 沸点: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• 密度: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• 痕量阳离子: Pb: ≤0.05 ppm
• SMILES字符串: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

说明

一般描述

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have a narcotic effect.[1] It is susceptible to degradation with time, which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Low water content, minimal residue and clean UV spectra are the special characteristics of this biotech grade solvent. It can be utilized for biotechnological processes like protein sequencing, peptide and oligonucleotide synthesis. Reports suggest that chloroform stabilized with ethanol reduces chances on creating artifacts during the chromatographic separation after extraction of anthracyclines from biological matrices.[2]

应用

Chloroform may be used in the following processes:

• Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).[3]
• Preparing phospholipid solutions.[4]
• As a solvent in the photolysis reaction of ruthenium complexes.[5]
• Solvent for recrystallization.[6]
• Reference compound to detect the presence of chloroform in Tobacco smokes.[7]
• Extractant in solvent extraction process.[8]

安全信息

• 象形图: GHS06,GHS08
• 警示用语：: Danger
• 危险声明: H302,H315,H319,H331,H336,H351,H361d,H372
• 预防措施声明: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• 危险分类: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• 靶器官: Central nervous system, Liver,Kidney
• 储存分类代码: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 闪点(°F): does not flash
• 闪点(°C): does not flash