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Merck

D8064

Sigma-Aldrich

氢氧化4-(2-(6-(二丁基氨基)-2-萘基)乙烯基)-1-(3-磺丙基)吡啶鎓 内盐

≥95% purity (HPLC), solid

别名:

Di-4-ANEPPS

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About This Item

经验公式(希尔记法):
C28H36N2O3S
CAS号:
分子量:
480.66
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
价格与库存信息目前不能提供

产品名称

氢氧化4-(2-(6-(二丁基氨基)-2-萘基)乙烯基)-1-(3-磺丙基)吡啶鎓 内盐, ≥95% (HPLC), solid

质量水平

方案

≥95% (HPLC)

表单

solid

分子量

480.66

技术

titration: suitable

颜色

orange to dark red

溶解性

DMF: soluble
DMSO: soluble
ethanol: soluble

ε (消光系数)

≥38000 at 493-499 nm in methanol

应用

diagnostic assay manufacturing
hematology
histology

储存温度

2-8°C

SMILES字符串

CCCCN(CCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1

InChI

1S/C28H36N2O3S/c1-3-5-17-30(18-6-4-2)28-13-12-26-22-25(10-11-27(26)23-28)9-8-24-14-19-29(20-15-24)16-7-21-34(31,32)33/h8-15,19-20,22-23H,3-7,16-18,21H2,1-2H3

InChI key

HAPJROQJVSPKCJ-UHFFFAOYSA-N

应用

氢氧化 4-(2-(6-(二丁基氨基)-2-萘基)乙烯基)-1-(3-硫代丙基)吡啶正离子内盐已用作心脏细胞中的电压敏感染料。[1]

生化/生理作用

膜电位染料,可响应在 440 和 505 nm 处荧光激发监测的膜电位的变化;与细胞膜电位的变化有关。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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G Bub et al.
American journal of physiology. Heart and circulatory physiology, 298(5), H1616-H1625 (2010-03-17)
Sarcomere length (SL) is an important determinant and indicator of cardiac mechanical function; however, techniques for measuring SL in living, intact tissue are limited. Here, we present a technique that uses two-photon microscopy to directly image striations of living cells
J M Davidenko et al.
Nature, 355(6358), 349-351 (1992-01-23)
Excitable media can support spiral waves rotating around an organizing centre. Spiral waves have been discovered in different types of autocatalytic chemical reactions and in biological systems. The so-called 're-entrant excitation' of myocardial cells, causing the most dangerous cardiac arrhythmias
Stefano Casali et al.
Communications biology, 3(1), 635-635 (2020-11-01)
Long-term synaptic plasticity is thought to provide the substrate for adaptive computation in brain circuits but very little is known about its spatiotemporal organization. Here, we combined multi-spot two-photon laser microscopy in rat cerebellar slices with realistic modeling to map
Zachary Laksman et al.
Scientific reports, 7(1), 5268-5268 (2017-07-15)
Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We generated atrial-like cardiomyocytes (CMs) from hESCs which preferentially expressed atrial-specific
James E Reeve et al.
Biophysical journal, 103(5), 907-917 (2012-09-27)
Numerous dyes are available or under development for probing the structural and functional properties of biological membranes. Exogenous chromophores adopt a range of orientations when bound to membranes, which have a drastic effect on their biophysical behavior. Here, we present

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