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About This Item
经验公式（希尔记法）:
C36H52N2O3S
CAS号:
分子量:
592.87
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47
价格与库存信息目前不能提供
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产品名称
4-(2-[6-(二辛基氨基)-2-萘基]乙烯基)-1-(3-磺丙基)吡啶鎓 内盐, ≥95% (HPLC), solid
品質等級
化驗
≥95% (HPLC)
形狀
solid
分子量
592.88
顏色
orange to red
溶解度
DMSO: soluble
ethanol: soluble
&epsilon ；(消光係數)
≥37 at 495-501 nm in methanol
螢光
λex 710-716 nm
應用
diagnostic assay manufacturing
hematology
histology
儲存溫度
2-8°C
SMILES 字串
CCCCCCCCN(CCCCCCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1
InChI
1S/C36H52N2O3S/c1-3-5-7-9-11-13-25-38(26-14-12-10-8-6-4-2)36-21-20-34-30-33(18-19-35(34)31-36)17-16-32-22-27-37(28-23-32)24-15-29-42(39,40)41/h16-23,27-28,30-31H,3-15,24-26,29H2,1-2H3
InChI 密鑰
IXFSUSNUALIXLU-UHFFFAOYSA-N
生化／生理作用
一种快速响应的膜电位染料。
聯結
可在细胞质膜外叶滞留更久，因此比di-4-ANEPPS（货号D8064）更适合长时程膜电位研究。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Sanaya N Shroff et al.
iScience, 23(4), 100974-100974 (2020-04-17)
Precise measurement of action potentials (APs) is needed to observe electrical activity and cellular communication within cardiac tissue. Voltage-sensitive dyes (VSDs) are traditionally used to measure cardiac APs; however, they require acute chemical addition that prevents chronic imaging. Genetically encoded
Antonio Celestino-Montes et al.
Life sciences, 264, 118700-118700 (2020-11-02)
Ventricular myocytes (VM) depolarization activates L-type Ca2+ channels (LCC) allowing Ca2+ influx (ICa) to synchronize sarcoplasmic reticulum (SR) Ca2+ release, via Ca2+-release channels (RyR2). The resulting whole-cell Ca2+ transient triggers contraction, while cytosolic Ca2+ removal by SR Ca2+ pump (SERCA2)
Carlos A Valverde et al.
Cardiovascular research, 115(3), 556-569 (2018-09-01)
Abnormal Ca2+ release from the sarcoplasmic reticulum (SR), associated with Ca2+-calmodulin kinase II (CaMKII)-dependent phosphorylation of RyR2 at Ser2814, has consistently been linked to arrhythmogenesis and ischaemia/reperfusion (I/R)-induced cell death. In contrast, the role played by SR Ca2+ uptake under
S Antić et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 15(2), 1392-1405 (1995-02-01)
We carried out experiments to monitor optically the generation and spread of action potentials and subthreshold potentials in the processes of individual neurons in ganglia of the snail, Helix aspersa. The neurons were selectively stained by intracellular pressure injection of
Kirby R Campbell et al.
The journal of physical chemistry. B, 121(8), 1749-1757 (2017-02-09)
Extensive remodeling of the extracellular matrix (ECM) occurs in many epithelial cancers. For example, in ovarian cancer, upregulation of collagen isoform type III has been linked to invasive forms of the disease, and this change may be a potential biomarker.
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