1.08307

高纯度三(羟甲基)胺基甲烷(氨基丁三醇)

(Trometamol) high purity, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JPC, USP

• 别名: 三（羟甲基）氨基甲烷, 2-氨基-2-(羟甲基)-1,3-丙二醇, THAM, Tris 碱, 氨基丁三醇
• 线性分子式: NH₂C(CH₂OH)₃
• CAS号: 77-86-1
• 分子量: 121.14
• Beilstein: 741883
• MDL编号: MFCD00004679
• UNSPSC代码: 12352209
• EC索引号: 201-064-4

属性

• Agency: BP; ChP; JPC; Ph. Eur.; USP
• 质量水平: 500
• 蒸汽压: 0.0267 hPa ( 20 °C)
• 描述: EMPROVE^® EXPERT Ph Eur,BP,JPC,USP,ACS
• 产品线: EMPROVE^® EXPERT
• 表单: solid
• 特点: RNase and DNase free
• pH值（酸碱度）: 10.2-10.6 (20 °C, 6 g/L in H₂O)
• 有效pH范围: 7-9
• pKa (25 °C): 8.1
• 沸点: 219-220 °C/10 mmHg (lit.); 219-220 °C/13.3 hPa
• mp: 167-172 °C (lit.)
• 密度: 1.35 g/cm³ at 23 °C
• 应用: liquid formulation; pharmaceutical; semi-solid formulation
• 储存温度: no temp limit
• SMILES字符串: NC(CO)(CO)CO
• InChI: 1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
• InChI key: LENZDBCJOHFCAS-UHFFFAOYSA-N

说明

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Tris(hydroxymethyl)aminomethane (Trometamol) is a commonly used buffer component in biomolecule downstream chromatography steps as well as final liquid formulation.
Due to its low polyoxymethylene limits, Tris(hydroxymethyl)aminomethane (Trometamol) Emprove^® Expert is suitable for use at elevated concentrations without risking precipitation. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable