Yes, a dilution series of HPLC-grade chitosan can be made for HPLC analysis to establish a calibration curve for quantification. However, no molecular weight information is available.
价格与库存信息目前不能提供
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质量水平
表单
powder
分子量
50,000-190,000 Da (based on viscosity)
粘度
20-300 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)
溶解性
dilute aqueous acid: soluble
SMILES字符串
N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5N)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6N)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7N)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8N)O)O[C@@H]9O[C@@H]([C@H](
InChI
1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1
InChI key
FLASNYPZGWUPSU-SICDJOISSA-N
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应用
与多价阴离子形成凝胶。 产生透明溶液，干燥后形成坚固、透明的薄膜。
壳聚糖可用于蛋白质沉淀中的凝聚剂、包封剂和水性增稠剂。
特点和优势
生物相容、抗菌和环保的聚电解质，其具有多种应用，包括水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。
生物相容性、抗菌和环保的聚电解质。
外形
75-85% 脱乙酰化
储存分类代码
11 - Combustible Solids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Ming-Hui Yang et al.
BioMed research international, 2014, 789591-789591 (2014-04-24)
Chitosan nanoparticle, a biocompatible material, was used as a potential drug delivery system widely. Our current investigation studies were the bioeffects of the chitosan nanoparticle uptake by liver cells. In this experiment, the characterizations of chitosan nanoparticles were measured by
Ajay Vijayakumar et al.
AAPS PharmSciTech, 18(3), 875-883 (2016-07-03)
The objective of this study was to formulate and characterize properties of solid lipid nanoparticle (SLN) dispersion containing quercetin. SLN was prepared by ultrasonication method using tripalmitin and lecithin as lipid core and then the surface was coated with chitosan.
Tsung-Lin Yang et al.
Journal of cellular and molecular medicine, 13(9A), 2853-2863 (2008-07-17)
Chitosan is a widely used biocompatible biomaterial in the tissue regeneration, but its utility and application in the tissue morphogenesis of salivary gland remains unclear. The study aimed to explore the effects of chitosan on the epithelial morphogenesis of submandibular
Wei-Hsuan Lo et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-07)
(1) Background: Few antifungal drugs are currently available, and drug-resistant strains have rapidly emerged. Thus, the aim of this study is to evaluate the effectiveness of the antifungal activity from a combinational treatment of chitosan with a clinical antifungal drug
Mar Collado-González et al.
Marine drugs, 18(1) (2020-01-19)
Polyelectrolyte nanocomposites rarely reach a stable state and aggregation often occurs. Here, we report the synthesis of nanocomposites for the oral delivery of insulin composed of alginate, dextran sulfate, poly-(ethylene glycol) 4000, poloxamer 188, chitosan, and bovine serum albumin. The
商品
Carcinogenic compounds in elastomers: 1,3-butadiene and isoprene used in elastomer manufacturing, classified as carcinogenic by IARC.
Carcinogenic compounds in elastomers: 1,3-butadiene and isoprene used in elastomer manufacturing, classified as carcinogenic by IARC.
Polymers, natural or synthetic, are vital in medical advancements, contributing to device and pharmaceutical development in therapy.
Polymers, natural or synthetic, are vital in medical advancements, contributing to device and pharmaceutical development in therapy.
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Dear Sir, could I make a dilution serious of HPLC Chitosan and analysis through HPLC for quantification and calibration curve? and what molecular weight should I use for 250 microgram/mL stock solution?
1 answer-
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Dear sir Could we get the (HNMR) and viscosity testing for the determination of the degree of deacetylated chitosan as we used the one with "(50,000–190,000 Da and degree of deacetylation equal or greater than 70%.Polymers Journal requested it.
1 answer-
The result for the degree of deacetylation is provided on the certificate of analysis for each lot of this product. Unfortunately, the assay method may not be shared.
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Can i use this Chitosan for fruit coating?
1 answer-
This product is intended for research use only and is not food grade. Therefore it is not recommended for a fruit coating application.
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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We need to confirm if this Chitosan (Catalog #448869) is of animal origin (shellfish) or synthetic.
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The source information is located on the Certificate of Origin and may vary from lot to lot. Recent lot shows the source of this product is from the shells of Pandalus Borealis, Cold Water Shrimp.
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What is the molecular weight (Mw) of products 448869, 448877, or 419419?
1 answer-
The molecular weight (Mw) of products 448869, 448877, and 419419 are approximately 150-250 kDa, 250-300 kDa, and 340-360 kDa, respectively. These values are calculated based on the viscosity values provided on the product data sheets and the corresponding table of viscosity vs Mw.
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What are the Mark-Houwink–Sakurada parameters (K and alpha) you use for determination of molecular weight through viscosity? Thank you!
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The Certificates of Analysis(CofA) for each lot of Product 448869, a low molecular weight Chitosan, do not report a molecular weight. However, the viscosity in 1 percent acetic acid (abbreviated HAc or HOAc) is on the CofA. Values for K and alpha for high molecular weight Chitosan have been published, which might also apply to a low molecular weight Chitosan; see Calculation of Mark–Houwink–Sakurada (MHS) equation viscometric constants for chitosan in any solvent–temperature system using experimentally reported viscometric constants data, by Mohammed R. Kasaai. Carbohydrate Polymers, 68(3), 477-488 (2007).
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Is this analytical grade?
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This product is not considered analytical grade. It is intended for general research use. Currently, no analytical grade product option is available.
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Is it research or food grade? Thanks
1 answer-
This product is intended for research use only. Currently, there is no food-grade product option available
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