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Merck

225827

Sigma-Aldrich

N,N′-二琥珀酰亚胺碳酸酯

≥95%, for peptide synthesis

别名:

N-琥珀酰氨基碳酸酯, DSC, 二(N-琥珀酰亚胺基)碳酸酯

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About This Item

经验公式(希尔记法):
C9H8N2O7
CAS号:
分子量:
256.17
Beilstein:
1499137
EC號碼:
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.22
价格与库存信息目前不能提供

产品名称

N,N′-二琥珀酰亚胺碳酸酯, ≥95%

品質等級

化驗

≥95%

形狀

powder or crystals

反應適用性

reaction type: Carbonylations

mp

190 °C (dec.) (lit.)

應用

peptide synthesis

官能基

imide

儲存溫度

2-8°C

SMILES 字串

O=C1CCC(=O)N1OC(=O)ON2C(=O)CCC2=O

InChI

1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2

InChI 密鑰

PFYXSUNOLOJMDX-UHFFFAOYSA-N

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一般說明

N,N′-碳酸二琥珀酰亚胺酯可用于通过HPLC对氨基化合物进行测定。

應用

N,N′-碳酸二琥珀酰亚胺酯可用于:
  • 作为活化剂,通过后官能化将聚合物刷与伯胺进行偶联,从而用于改变其反应模式。[1]
  • 作为多种伯醇和空间受阻的仲醇的烷氧羰基化试剂,它还可以用于合成结构上不同的氨基甲酸酯。[2]
  • 作为合成硫代磷脂的偶联剂,通常可用于将生物膜固定在金表面。[3]
它也可用于制备硫醇修饰DNA的连接子,该连接子是一种异双功能、可裂解的SVEC(琥珀酰亚胺乙烯基磺酰氨基乙基碳酸酯)。

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT RE 2 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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N,N?-Disuccinimidyl carbonate as a coupling agent in the synthesis of thiophospholipids used for anchoring biomembranes to gold surfaces
Boden N, et al.
Tetrahedron, 54(38), 11537-11548 (1998)
Tetrahedron Letters, 33, 2781-2781 (1992)
N, N?-Disuccinimidyl Carbonate: A Useful Reagent for Alkoxycarbonylation of Amines
Ghosh KA, et al.
Tetrahedron Letters, 33(20), 2781-2781 (1992)
Chang-Juan Tao et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 115(3), 407-411 (2015-05-31)
To assess whether consensus guideline-based atlas-based auto-segmentation (ABAS) reduces interobserver variation and improves dosimetric parameter consistency for organs at risk (OARs) in nasopharyngeal carcinoma (NPC). Eight radiation oncologists from 8 institutes contoured 20 OARs on planning CT images of 16
Reactive patterning via post-functionalization of polymer brushes utilizing disuccinimidyl carbonate activation to couple primary amines
Diamanti S, et al.
Polymer, 49(17), 3770-3779 (2008)

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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