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Merck

SML1792

Sigma-Aldrich

Oxazole yellow

≥98% (HPLC)

Synonym(e):

4-[(3-Methyl-2(3H)-benzoxazolylidene)methyl]-1-[3-(trimethylammonio)propyl]-quinolinium diiodide

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About This Item

Empirische Formel (Hill-System):
C24H29I2N3O
CAS-Nummer:
Molekulargewicht:
629.32
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77

Qualitätsniveau

Assay

≥98% (HPLC)

Form

powder

Lagerbedingungen

protect from light

Farbe

yellow to orange-brown

Löslichkeit

H2O: 5, clear (warmed)

Lagertemp.

2-8°C

SMILES String

CN1C2=CC=CC=C2OC1=CC3=CC=[N+](CCC[N+](C)(C)C)C4=C3C=CC=C4

InChI

1S/C24H29N3O.2HI/c1-25-22-12-7-8-13-23(22)28-24(25)18-19-14-16-26(15-9-17-27(2,3)4)21-11-6-5-10-20(19)21;;/h5-8,10-14,16,18H,9,15,17H2,1-4H3;2*1H/q+2;;/p-2

InChIKey

ULHRKLSNHXXJLO-UHFFFAOYSA-L

Biochem./physiol. Wirkung

Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.

Piktogramme

Skull and crossbones

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Andreas S Biebricher et al.
Nature communications, 6, 7304-7304 (2015-06-19)
DNA intercalators are widely used as fluorescent probes to visualize DNA and DNA transactions in vivo and in vitro. It is well known that they perturb DNA structure and stability, which can in turn influence DNA-processing by proteins. Here we
Sho Fujisawa et al.
Cytotechnology, 66(2), 259-273 (2013-09-26)
Radiofrequency (RF) ablation (RFA) is a minimally invasive treatment for colorectal-cancer liver metastases (CLM) in selected nonsurgical patients. Unlike surgical resection, RFA is not followed by routine pathological examination of the target tumor and the surrounding liver tissue. The aim

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