390062

Thiazol-Orange

Dye content ~90 %

• Synonym(e): 1-Methyl-4-[(3-methyl-2(3H)-benzothiazolyliden)-methyl]-chinolinium-p-tosylat
• Empirische Formel (Hill-System): C₂₆H₂₄N₂O₃S₂
• CAS-Nummer: 107091-89-4
• Molekulargewicht: 476.61
• MDL-Nummer: MFCD00192499
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24864313
• NACRES: NA.47

Eigenschaften

• Form: powder
• Qualitätsniveau: 200
• Zusammensetzung: Dye content, ~90%
• Methode(n): titration: suitable
• mp (Schmelzpunkt): 270 °C (dec.) (lit.)
• λmax: 512 nm
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: Cc1ccc(cc1)S([O-])(=O)=O.CN2C(\Sc3ccccc23)=C\c4cc[n+](C)c5ccccc45
• InChI: 1S/C19H17N2S.C7H8O3S/c1-20-12-11-14(15-7-3-4-8-16(15)20)13-19-21(2)17-9-5-6-10-18(17)22-19;1-6-2-4-7(5-3-6)11(8,9)10/h3-13H,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChIKey: ACOJCCLIDPZYJC-UHFFFAOYSA-M

Beschreibung

Allgemeine Beschreibung

Thiazole Orange can be tethered with peptide nucleic acid for the detection of target nucleic acid in homogeneous solution. It is a dye with, both predicted physical characteristics and the biological staining characteristics of a good reticulocyte dye, hence it is considered as a dye for reticulocyte analysis. It has massive fluorescence enhancement and high quantum yield upon binding to nucleic acids, particularly RNA. It is non precipitating and can permeates through live cell membranes.

Anwendung

Thiazole orange has been used for the staining and thereby quantification of reticulocytes.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves