S1542

Anti-Substance P antibody produced in rabbit

whole antiserum

• Synonym(e): Anti-SP
• MDL-Nummer: MFCD00162870
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: whole antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Enthält: 15 mM sodium azide
• Speziesreaktivität: human, pig, bovine, rat, cat, monkey
• Methode(n): dot blot: 1:20,000; radioimmunoassay: 1:5,000
• UniProt-Hinterlegungsnummer: P20366
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... TAC1(6863) ; rat ... Tac1(24806)

Beschreibung

Allgemeine Beschreibung

Substance P (SP) is a 11 amino acid peptide. It is a member of tachykinins family, that includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1 It is located on human chromosome 7q21.3.

Substance P (SP) is widely distributed throughout the central nervous system (CNS) and peripheral nervous system, including the brain, spinal cord, primary sensory neurons and intrinsic nerve fibers associated with the gastrointestinal (GI) tract.

Immunogen

synthetic Substance P (SP), conugated to KLH.

Anwendung

Anti-Substance P antibody has been used in immunostaining and immunohistochemistry.

Biochem./physiol. Wirkung

Substance P (SP) improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, trigger glandular secretion and controls autonomic reflexes. It plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.

Substance P (SP) is a neurotransmitter or neuromodulator. SP mediates the process of neurogenic inflammation.

Hinweis zur Analyse

The antiserum is evaluated for activity and specificity by dot blot immunoassay and RIA.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable