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G5262

Supelco

GAPDH

standard for protein electrophoresis

Synonym(e):

Glyceraldehyd-3-Phosphat-Dehydrogenase aus Kaninchenmuskel, GAP-DH

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About This Item

CAS-Nummer:
9001-50-7
EC-Nummer:
1.2.1.12 (BRENDA, IUBMB)
EG-Nummer:
232-609-4
MDL-Nummer:
MFCD00131203
UNSPSC-Code:
12352204
NACRES:
NA.32

Qualität

for molecular biology

Qualitätsniveau

200

Form

powder

Mol-Gew.

~36 kDa

Verpackung

vial of 5 mg

Methode(n)

electrophoresis: suitable

Lagertemp.

2-8°C

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Allgemeine Beschreibung

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) catalyzes the conversion of glyceraldehyde-3-phosphate into D-glycerate-1,3-bisphosphate as part of the glycolysis pathway. GAPDH has also been found to function in additional cellular process, such as transcription, apoptosis, oxidative stress and ER to Golgi transport.

Anwendung

GAPDH protein is suitable for use as a molecular weight marker and protein standard for molecular biology applications, including western blotting and mass spectometry.

Biochem./physiol. Wirkung

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate into D-glycerate-1,3-bisphosphate as part of the glycolysis pathway.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Ling Ji et al.
Molecular therapy. Nucleic acids, 19, 546-561 (2020-01-14)
Long non-coding RNAs (lncRNAs) are crucial molecules in tumorigenesis and tumor growth in various human cancers, including colorectal cancer (CRC). Studies have revealed that lncRNAs can regulate cellular processes in cancers by interacting with proteins, for example RNA-binding proteins (RBPs).
Craig Nicholls et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(33), 13308-13313 (2012-08-01)
Oxidative stress regulates telomere homeostasis and cellular aging by unclear mechanisms. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a key mediator of many oxidative stress responses, involving GAPDH nuclear translocation and induction of cell death. We report here that GAPDH interacts with
Xiaopeng Wang et al.
Molecular medicine reports, 23(2) (2020-12-11)
Acute progressive hypoxic respiratory failure caused by various predisposing factors is known as acute respiratory distress syndrome (ARDS). Although penehyclidine hydrochloride (PHC), an anticholinergic drug, is widely applied in clinical practice, the specific mechanisms underlying PHC in the treatment of
Joyce Jing Yi Wong et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(28), 10735-10740 (2006-07-04)
Type I IFNs induce the expression of IFN-stimulated gene 15 (ISG15) and its conjugation to cellular targets. ISGylation is a multistep process involving IFN-inducible Ube1L, UbcH8, and a yet-to-be identified E3 ligase. Here we report the identification of an IFN-induced
Kati Juuti-Uusitalo et al.
Investigative ophthalmology & visual science, 54(5), 3510-3519 (2013-05-21)
Aquaporins (AQPs), a family of transmembrane water channel proteins, are essential for allowing passive water transport through retinal pigmented epithelial (RPE) cells. Even though human native RPE cells and immortalized human RPEs have been shown to express AQPs, the expression
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