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G6019

Sigma-Aldrich

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

lyophilized powder, 50-150 units/mg protein

Synonym(e):

D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH

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About This Item

CAS-Nummer:
9001-50-7
EC-Nummer:
1.2.1.12 (BRENDA, IUBMB)
MDL-Nummer:
MFCD00131203
UNSPSC-Code:
12352204
NACRES:
NA.54

Form

lyophilized powder

Qualitätsniveau

200

Spezifische Aktivität

50-150 units/mg protein

Zusammensetzung

Protein, 40-70% biuret

UniProt-Hinterlegungsnummer

P04406

Fremdaktivität

3-Phosphoglyceric phosphokinase ≤2%

Lagertemp.

−20°C

Angaben zum Gen

human ... GAPDH(2597)

Biochem./physiol. Wirkung

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.

Einheitendefinition

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.

Physikalische Form

Lyophilized powder containing sodium citrate buffer salts

Inhibitor

Produkt-Nr.
Beschreibung
Preisangaben

I2512

Natriumjodacetat, ≥98%

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Michele Salemi et al.
Tumori, 98(3), 86e-88e (2012-07-25)
Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers in the world. Risk factors for this cancer include tobacco and alcohol use, ultraviolet light exposure, and viral infection. Parkinson's disease is one of the most
Anne Gürtler et al.
Analytical biochemistry, 433(2), 105-111 (2012-10-23)
Western blots are used to specifically measure the relative quantities of proteins of interest in complex biological samples. Quantitative measurements can be subject to error due to process inconsistencies such as uneven protein transfer to the membrane. These non-sample-related variations
Kyle L Sunderland et al.
Journal of strength and conditioning research, 27(1), 1-7 (2012-10-23)
The purpose of this study was to investigate how age and 1 week of conventional resistance exercise affects commonly used housekeeping gene (HKG) messenger RNAs (mRNAs) in skeletal muscle. Ten college-aged (18-25 years) and 10 older (60-76 years) men completed
Soya S Sam et al.
Pathology, research and practice, 208(12), 705-707 (2012-10-13)
Isolation of DNA from formalin-fixed, paraffin-embedded (FFPE) tissue remains a laborious task for clinical laboratories and researchers who need to screen several samples for genetic variants. The objective of this study was to evaluate DNA isolation methods from FFPE tissues
Qiao Liu et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 8), 978-980 (2012-08-08)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces
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