C0567

(−)-Catechin

from green tea, ≥97% (HPLC), powder, oxidative stress inhibitor

• Synonym(e): (−)-trans-3,3′,4′,5,7-Pentahydroxy-flavan, (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
• Empirische Formel (Hill-System): C₁₅H₁₄O₆
• CAS-Nummer: 18829-70-4
• Molekulargewicht: 290.27
• EG-Nummer: 242-611-7
• MDL-Nummer: MFCD00135997
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24892260
• NACRES: NA.77

Eigenschaften

• Produktbezeichnung: (−)-Catechin, ≥97% (HPLC), from green tea
• Biologische Quelle: green tea
• Qualitätsniveau: 200
• Assay: ≥97% (HPLC)
• Form: powder
• Lagertemp.: 2-8°C
• SMILES String: O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)c(O)c3
• InChI: 1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
• InChIKey: PFTAWBLQPZVEMU-HIFRSBDPSA-N
• Angaben zum Gen: human ... BACE1(23621)

Beschreibung

Allgemeine Beschreibung

Catechins are major flavonoids present in green tea accounting to 90%. (−)-catechin is comparatively less bioavailable than the (+)-catechin for intestinal absorption.

Anwendung

(-)-Catechin has been used:

• to test its binding affinity towards estrogen receptor
• as a reference standard in high-performance liquid chromatography for quantification of polyphenols from plant extracts (HPLC)
• as a reference standard in kinetic studies to quantify antioxidants from Iranian green tea leaves

Biochem./physiol. Wirkung

Catechins have wide biological functionality. They induce antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. It prevents fat accumulation.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)