QBD10501

Azido-dPEG^®₄-NHS ester

• Synonym(e): 3-(Azidotetra(ethyleneoxy))propionic acid succinimidyl ester, NHS-Peg4-Azide, Polyethylene glycol
• Empirische Formel (Hill-System): C₁₅H₂₄N₄O₈
• CAS-Nummer: 944251-24-5
• Molekulargewicht: 388.37
• MDL-Nummer: MFCD13184948
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 329823930
• NACRES: NA.22

Eigenschaften

• Assay: >90%
• Form: solid or viscous liquid
• Eignung der Reaktion: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• Funktionelle Gruppe: NHS ester; azide
• Polymerarchitektur: shape: linear; functionality: heterobifunctional
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-]
• InChI: 1S/C15H24N4O8/c16-18-17-4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(22)27-19-13(20)1-2-14(19)21/h1-12H2
• InChIKey: OIGKWPIMJCPGGD-UHFFFAOYSA-N

Beschreibung

Leistungsmerkmale und Vorteile

The azido-dPEG^®₄-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. NHS ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Rechtliche Hinweise

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable