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Wichtige Dokumente
P38706
Phthalazin
98%
Synonym(e):
β-Phenodiazine, 2,3-Benzodiazine, 2,3-Diazanaphthalene, Benzo[d]pyridazine
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Alle Fotos(3)
About This Item
Empfohlene Produkte
Qualitätsniveau
Assay
98%
Form
crystals
bp
189 °C/29 mmHg (lit.)
mp (Schmelzpunkt)
89-92 °C (lit.)
Lagertemp.
2-8°C
SMILES String
c1ccc2cnncc2c1
InChI
1S/C8H6N2/c1-2-4-8-6-10-9-5-7(8)3-1/h1-6H
InChIKey
LFSXCDWNBUNEEM-UHFFFAOYSA-N
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Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Aquatic Chronic 3 - Muta. 2
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Investigations into the structure-activity relationships (SAR) of a series of phthalazine-based inhibitors of p38 are described. These efforts originated from quinazoline 1 and through rational design led to the development of a series of orally bioavailable, potent, and selective inhibitors.
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