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Merck

30906

Sigma-Aldrich

Rizinusöl, ethoxyliert

Synonym(e):

Cremophor® ELP, Polyoxyl-35 castor oil

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161900
NACRES:
NA.25

Beschreibung

non-ionic

Qualitätsniveau

Form

paste

Verunreinigungen

alkalinity, complies
≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only)
≤0.1% oleic acid
≤0.1% palmitic acid
≤0.2% sulfated ash (verfied on random samples only)
≤0.20% ricinoleic acid
≤0.5% water
≤1 ppm ethylene oxide (verfied on random samples only)
≤1.0% free fatty acids
≤10 ppm dioxan (verfied on random samples only)
≤10 ppm heavy metals (verfied on random samples only)
≤620 ppm diethylene glycol (verfied on random samples only)
≤620 ppm ethylene glycol (verfied on random samples only)

Glührückstand

≤0.2%

pH-Wert

5.0-7.0 (1 g/10 mL in H2O)

Viskosität

600-750 mPa.s(25 °C)

Säurezahl

≤2.0 mg KOH/g

Hydroxylzahl

65‑78 mg KOH/g

Iodzahl

25‑35 g/100g

Verseifungszahl

65‑70 mg KOH/g

Kationenspuren

K: ≤15 ppm

SMILES String

ClCC(OC(=O)N)CCl

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChIKey

JMNCUXPHXKHBPY-UHFFFAOYSA-N

Anwendung

Castor Oil, Ethoxylated is used to emulsify and solubilize oils and other water-insoluble substances. Similar to Castor Oil, Ethoxylated but with lower water content and differences in viscosity.

Hinweis zur Analyse

relative density D (25/25) 1.05-1.06

Rechtliche Hinweise

Cremophor is a registered trademark of BASF SE

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

494.6 °F - Not applicable

Flammpunkt (°C)

257 °C - Not applicable


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Oil-in-water emulsions are potent human adjuvants commonly used in effective pandemic influenza vaccines; however, such emulsions that can induce both Th1-biased systemic immune responses and strong mucosal immune responses via an easy method of administration are lacking. To address this
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ABI-007 is a novel Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. The absence of Cremophor EL may permit ABI-007 to be administered without the premedications used routinely for the prevention of hypersensitivity reactions. Furthermore, this novel formulation permits a higher paclitaxel

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