286583

5-Methoxytryptamin

97%

• Synonym(e): 3-(2-Aminoethyl)-5-methoxy-indol
• Empirische Formel (Hill-System): C₁₁H₁₄N₂O
• CAS-Nummer: 608-07-1
• Molekulargewicht: 190.24
• Beilstein: 145587
• EG-Nummer: 210-153-7
• MDL-Nummer: MFCD00005662
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24857245
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 97%
• Form: solid
• mp (Schmelzpunkt): 121-123 °C (lit.)
• Funktionelle Gruppe: amine
• SMILES String: COc1ccc2[nH]cc(CCN)c2c1
• InChI: 1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
• InChIKey: JTEJPPKMYBDEMY-UHFFFAOYSA-N
• Angaben zum Gen: human ... HTR1A(3350) , HTR2A(3356) , HTR2C(3358) ; rat ... Htr2a(29595) , Htr2c(25187) , Htr7(65032)

Beschreibung

Allgemeine Beschreibung

The protective effect of 5-methoxytryptamine (a metabolite of melatonin) in human keratinocytes against ultraviolet B (UVB) radiation was studied.

Anwendung

5-Methoxytryptamine was used as an agonist in the study of pharmacological profile of the 5-hydroxytryptamine 1 receptor.

Reactant for preparation of:

• Carboline disaccharide domain of shishijimicin A
• Melatonin analogs for the reduction of intraocular pressure
• 5-HT4 receptor ligands
• inhibitors of sortase A and isocitrate lyase
• Therapeutic agents for treatment of ischemia/reperfusion (I/R) injury
• Aurora and epidermal growth factor receptor kinase inhibitors
• Agents for the treatment of human papillomavirus infection
• Manzamine analogues for the control of neuroinflammation and cerebral infections
• Inhibitors of pro-inflammatory cytokines
• Tacrine-melatonin hybrids as multifunctional agents for alzheimer′s disease

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves