42085

1-Fluor-2,4-Dinitrobenzol

purum p.a., ≥98.0% (GC)

• Synonym(e): 2,4-Dinitro-1-Fluorbenzol, DNFB, FDNB, Sanger-Reagens
• Lineare Formel: (O₂N)₂C₆H₃F
• CAS-Nummer: 70-34-8
• Molekulargewicht: 186.10
• Beilstein: 398632
• EG-Nummer: 200-734-3
• MDL-Nummer: MFCD00007056
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 57650098
• NACRES: NA.22

Eigenschaften

• Qualität: purum p.a.
• Qualitätsniveau: 100
• Assay: ≥98.0% (GC)
• Form: liquid
• Brechungsindex: n20/D 1.569 (lit.)
• bp: 178 °C/25 mmHg (lit.)
• mp (Schmelzpunkt): 25-27 °C (lit.)
• Dichte: 1.482 g/mL at 25 °C (lit.)
• Kationenspuren: Ca: ≤50 mg/kg; Cd: ≤50 mg/kg; Co: ≤50 mg/kg; Cu: ≤50 mg/kg; Fe: ≤50 mg/kg; K: ≤100 mg/kg; Na: ≤100 mg/kg; Ni: ≤50 mg/kg; Pb: ≤50 mg/kg; Zn: ≤50 mg/kg
• Funktionelle Gruppe: fluoro; nitro
• Lagertemp.: 2-8°C
• SMILES String: [O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O
• InChI: 1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H
• InChIKey: LOTKRQAVGJMPNV-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Fluoro-2,4-dinitrobenzene(FDNB, Sanger′s reagent) is used to identify the amino acid sequence. Thischemical is used to label the free amino groups in proteins and peptides. Itcan also be used to protect the amine group, and for phenol deoxygenation. Additionally,it is a very helpful reagent for nucleophilic substitution reactions tointroduce a chromophore group to amines, phenols, and thiols.

Anwendung

1-Fluoro-2,4-dinitrobenzene is used as a derivatization agent:

• For aminoglycoside compounds such as amikacine, tobramycine, gentamycine, sisomycine, neamine, neomycine-B and neomycine-C.

1-Fluoro-2,4-dinitrobenzene can also be used:

• To examine the kinetic analysis and analytical uses of reaction with thiols in the presence of several surfactants.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H317,H319,H335,H373
• P-Sätze: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P314
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 327.2 °F
• Flammpunkt (°C): 164 °C
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves