417246

Dimethylzink -Lösung

1.0 M in heptane

• Synonym(e): Dimethylzinc
• Lineare Formel: (CH₃)₂Zn
• CAS-Nummer: 544-97-8
• Molekulargewicht: 95.46
• Beilstein: 3587195
• MDL-Nummer: MFCD00014854
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24866132
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Qualitätsniveau: 100
• Konzentration: 1.0 M in heptane
• bp: 44-46 °C
• Dichte: 0.724 g/mL at 25 °C
• SMILES String: C[Zn]C
• InChI: 1S/2CH3.Zn/h2*1H3;
• InChIKey: AXAZMDOAUQTMOW-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Dimethylzinc (Zn(CH₃)₂) is a methylating reagent used to prepare methylated organic compounds as well as organometallic compounds containing methyl groups . It is also utilized as a reagent to prepare amino alcohols, oximes, and hydrazones from arylamines, alkoxyamines, and dialkylhydrazines respectively, by radical addition reaction in the presence of air and THF.

Dimethylzinc is a diorganozinc reagent and nucleophile used in the synthesis of propargylic amines.

Anwendung

Dimethylzinc solution can be used as:

• A catalyst with nickel for the stereoselective C−2 alkenylation and dialkenylation of pyridine derivatives by alkynes to give monoalkenylation products.
• A reagent with aldehydes and 2-methoxyaniline for the synthesis of enantioselective alkyl and aralkyl secondary amines via one-pot three-component coupling reaction in the presence of zirconium tetraisopropoxide.
• A methylating reagent for methylation of fluoroalkylated pyruvates in the presence of copper/chiral diphosphine catalyst.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H225,H250,H261,H304,H314,H336,H410
• P-Sätze: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 2
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 30.2 °F - closed cup
• Flammpunkt (°C): -1 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles