SML0180

Aceclidine hydrochloride

≥98% (HPLC)

• 동의어(들): 1-Azabicyclo[2.2.2]oct-3-yl acetate hydrochloride, 3-Acetoxyquinuclidine hydrochloride
• 실험식(Hill 표기법): C₉H₁₅NO₂ · HCl
• CAS Number: 6109-70-2
• Molecular Weight: 205.68
• EC Number: 228-071-5
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825209
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to tan
• solubility: H₂O: ≥15 mg/mL at ~60 °C
• 저장 온도: −20°C
• SMILES string: Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2
• InChI: 1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1
• InChI key: LWWSARSTZGNKGV-FVGYRXGTSA-N

설명

애플리케이션

Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.

생화학적/생리학적 작용

Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.[1]

Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.[2]

Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.

Muscarinic receptor partial agonist

특징 및 장점

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311
• 예방조치 성명서: P264 - P280 - P301 + P310 - P302 + P352 + P312 - P361 + P364 - P405
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable