197602

Quinuclidine

97%

• 동의어(들): 1-Azabicyclo[2.2.2]octane, ABCO
• 실험식(Hill 표기법): C₇H₁₃N
• CAS Number: 100-76-5
• Molecular Weight: 111.18
• Beilstein: 103111
• EC Number: 202-887-1
• MDL number: MFCD00006690
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24851837
• NACRES: NA.22

속성

• vapor pressure: 1.5 mmHg ( 20 °C)
• Quality Level: 100
• 분석: 97%
• 양식: solid
• mp: 157-160 °C (lit.)
• solubility: H₂O: very slightly soluble; H₂O: very soluble; alcohol: miscible; diethyl ether: miscible; organic solvents: very soluble
• SMILES string: C1CN2CCC1CC2
• InChI: 1S/C7H13N/c1-4-8-5-2-7(1)3-6-8/h7H,1-6H2
• InChI key: SBYHFKPVCBCYGV-UHFFFAOYSA-N
• 유전자 정보: rat ... Chrm1(25229)

설명

일반 설명

Quinuclidine is a bicyclic tertiary amine with a bridgehead nitrogen atom structure, often used in the synthesis of iodonium complexes and as a hydrogen-atom-transfer (HAT) catalyst in photo induced reactions. [1]

애플리케이션

Quinuclidine can be used as a catalyst:

• In the Baylis-Hillman reaction of aldehydes with methyl acrylate[2].
• For the epimerization of α-methylglucose to α-methylallose[3].

It can also be used as a reactant to synthesize 5-[4-[2-(acetyloxy)ethyl]-1-piperidinyl]-2-pyridinecarbonitrile by reacting with 5-bromo-2-pyridinecarbonitrile in the presence of potassium acetate[4].

안전성 정보

• 픽토그램: GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H301,H310,H315,H318
• 예방조치 성명서: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges