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Merck
모든 사진(1)

문서

S0501

Sigma-Aldrich

Sodium nitroprusside dihydrate

동의어(들):

Nitroprusside sodium, SNP, Sodium nitroferricyanide, Sodium pentacyanonitrosylferrate

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About This Item

Linear Formula:
Na2[Fe(CN)5NO] · 2H2O
CAS Number:
Molecular Weight:
297.95
EC Number:
MDL number:
UNSPSC 코드:
12352300

SMILES string

O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;

InChI key

OIRZWVYIQXBRFC-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Releases NO in vivo, thus activating guanylyl cyclase, ADP-ribosyltransferase, and cyclooxygenase and inhibiting lipoxygenase. Induces vasodilation and inhibits platelet aggregation.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Feelisch, M.
Journal of Cardiovascular Pharmacology, 17, S25-S25 (1991)
C M Roos et al.
Journal of applied physiology (Bethesda, Md. : 1985), 77(1), 51-57 (1994-07-01)
We localized the sites of vasodilation of inhaled nitric oxide (NO), a selective pulmonary vasodilator, and sodium nitroprusside (SNP) in isolated rat lungs. The sites were determined by analyzing the arterial, venous, and double-occlusion data with a two-resistor (small arteries
F J Azula et al.
Molecular pharmacology, 50(2), 367-379 (1996-08-01)
Different drugs that elevate the cGMP levels inhibit the agonist-induced platelet activation. The mechanisms of action of cGMP probably include inhibition of both phospholipase C and the increase in intracellular Ca2+ concentration, and these effects seem to be mediated by
B Brüne et al.
The Journal of biological chemistry, 264(15), 8455-8458 (1989-05-25)
Sodium nitroprusside is a vasodilator and an inhibitor of platelet activation. It is thought that these effects are mediated by the spontaneous release of nitric oxide and stimulation of cytosolic guanylate cyclase. We have found that sodium nitroprusside (5-200 microM)
M Maccarrone et al.
Biochemical and biophysical research communications, 219(1), 128-133 (1996-02-06)
The nitric oxide (N0-releasing agents sodium nitroprusside (SNP) and S-nitroso-N-acetylpenicillamine (SNAP) inhibit dioxygenase activity of lipoxygenase in human platelets and human CHP100 neuroblastoma cells, leading the latter to necrosis. The effect of both NO-donors on the dioxygenase reaction was investigated

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