P0869
Monoclonal Anti-Peroxisome Proliferator Activated Receptor α antibody produced in mouse
~1 mg/mL, clone 3B6/PPAR, purified immunoglobulin, buffered aqueous solution
동의어(들):
Anti-PPARα
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크기 선택
100 μG
₩727,857
₩727,857
구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(1)
크기 선택
보기 변경
100 μG
₩727,857
About This Item
₩727,857
구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
3B6/PPAR, monoclonal
양식
buffered aqueous solution
종 반응성
mouse, rat, human
농도
~1 mg/mL
기술
western blot: 2-5 μg/mL using human, mouse and rat
동형
IgG2b
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PPARA(5465)
mouse ... Ppara(19013)
rat ... Ppara(25747)
일반 설명
Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.
면역원
purified recombinant PPARα protein.
생화학적/생리학적 작용
Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.
물리적 형태
Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Maria L R Hughes et al.
The Journal of biological chemistry, 290(22), 13895-13906 (2015-04-08)
Nuclear hormone receptors (NHRs) regulate the expression of proteins that control aspects of reproduction, development and metabolism, and are major therapeutic targets. However, NHRs are ubiquitous and participate in multiple physiological processes. Drugs that act at NHRs are therefore commonly
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
Be?atrice Desvergne and Walter Wahli
Endocrine Reviews, 20(5), 649?688-649?688 (1999)
Fenofibrate, a PPAR? agonist, protect proximal tubular cells from albumin-bound fatty acids induced apoptosis via the activation of NF-kB
Nan Zuo
International Journal of Clinical and Experimental Pathology, 8(9), 10653?10661-10653?10661 (2015)
C W Park et al.
Kidney international, 69(9), 1511-1517 (2006-05-05)
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a member of the ligand-activated nuclear receptor superfamily, and plays an important role in lipid metabolism and glucose homeostasis. The purpose of this study is to determine whether the activation of PPARalpha by fenofbrate
PPARs: molecular targets in the pharmacogenomics era
Prague Medical Report, 223-236 (2004)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
