H6166

Interferon α 2B human

IFN-α 2B, recombinant, expressed in HEK 293 cells, HumanKine^®, suitable for cell culture

• 동의어(들): IFN α 2B, IFN Alfa 2b, INF α 2B, INF Alfa 2b, Interferon Alfa 2b
• MDL number: MFCD01773210
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• 생물학적 소스: human
• Quality Level: 100
• 재조합: expressed in HEK 293 cells
• 분석: ≥95% (SDS-PAGE)
• 형태: lyophilized powder
• 효능: ≤0.12 ng/mL EC₅₀
• 품질: endotoxin tested
• 분자량: dimer 16 kDa (glycosylated)
• 포장: poly bottle of 10 μg (in poly bottle)
• 제조업체/상표: HumanZyme
• 기술: cell culture | mammalian: suitable
• 불순물: ≤1EU/mg
• UniProt 수납 번호: P01563
• 저장 온도: −20°C
• 유전자 정보: human ... IFNA2(3440)

설명

일반 설명

The interferon α 2 (IFN-α2) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five α helices. IFN-α2B is found structurally stable at pH 7. The recombinant IFN-α is nonglycosylated compared to the natural human IFN-α.

생화학적/생리학적 작용

Interferon α 2B (IFN-α 2B) belongs to the type I interferon protein family. It is produced by many cell types in response to viral infection. IFN-α 2B has antiproliferative and antitumor activities, as well as induction of apoptosis and the inflammatory response. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides and activates cytotoxic T-cells.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

제조 메모

HumanKine IFN-α 2B is a glycosylated monomer expressed in HEK 293 cells with an apparent molecular mass of 16 kDa. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

분석 메모

The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV ( vesicular stomatitis virus).

법적 정보

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable