์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck
๋ชจ๋“  ์‚ฌ์ง„(5)

์ฃผ์š” ๋ฌธ์„œ

G7879

Sigma-Aldrich

D-Glucose 6-phosphate sodium salt

โ‰ฅ98% (HPLC)

๋™์˜์–ด(๋“ค):

D(+)-Glucopyranose 6-phosphate sodium salt, G-6-P Na, Robison ester

๋กœ๊ทธ์ธ์กฐ์ง ๋ฐ ๊ณ„์•ฝ ๊ฐ€๊ฒฉ ๋ณด๊ธฐ

ํฌ๊ธฐ ์„ ํƒ

500 MG
โ‚ฉ120,075
1 G
โ‚ฉ172,347
5 G
โ‚ฉ592,557
25 G
โ‚ฉ1,548,281

โ‚ฉ120,075


์ถœ๊ณ  ๊ฐ€๋Šฅ์ผ2025๋…„ 4์›” 10์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

ํฌ๊ธฐ ์„ ํƒ

๋ณด๊ธฐ ๋ณ€๊ฒฝ
500 MG
โ‚ฉ120,075
1 G
โ‚ฉ172,347
5 G
โ‚ฉ592,557
25 G
โ‚ฉ1,548,281

About This Item

์‹คํ—˜์‹(Hill ํ‘œ๊ธฐ๋ฒ•):
C6H12NaO9P
CAS Number:
Molecular Weight:
282.12
Beilstein:
5787568
EC Number:
MDL number:
UNSPSC ์ฝ”๋“œ:
12352201
PubChem Substance ID:
NACRES:
NA.25

โ‚ฉ120,075


์ถœ๊ณ  ๊ฐ€๋Šฅ์ผ2025๋…„ 4์›” 10์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

์ƒ๋ฌผํ•™์  ์†Œ์Šค

synthetic (organic)

Quality Level

๋ถ„์„

โ‰ฅ98% (HPLC)

์–‘์‹

crystalline

๊ธฐ์ˆ 

HPLC: suitable

์ƒ‰์ƒ

white

์œ ์šฉํ•œ pH ๋ฒ”์œ„

4.0-5.0

mp

204ย ยฐC (dec.) (lit.)

solubility

water: 50ย mg/mL, clear, colorless to very faintly yellow

์–‘์ด์˜จ ๋ฏธ๋Ÿ‰๋ฌผ

Na: 6.1-10.2% (anhydrous)

์ €์žฅ ์˜จ๋„

room temp

SMILES string

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

InChI key

ZALKNDISPIVVKC-WYRLRVFGSA-M

์œ ์‚ฌํ•œ ์ œํ’ˆ์„ ์ฐพ์œผ์‹ญ๋‹ˆ๊นŒ? ๋ฐฉ๋ฌธ ์ œํ’ˆ ๋น„๊ต ์•ˆ๋‚ด

์• ํ”Œ๋ฆฌ์ผ€์ด์…˜

D-glucose-6-phosphate sodium can be used as an energy source for Mycobacterium tuberculosis. [1]

์ƒํ™”ํ•™์ /์ƒ๋ฆฌํ•™์  ์ž‘์šฉ

In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

์ฃผ์˜์‚ฌํ•ญ

Non-hygroscopic, and very stable to atmospheric moisture at room temperature, unlike the disodium salt.

๊ธฐํƒ€ ์ •๋ณด

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (ยฐF)

Not applicable

Flash Point (ยฐC)

Not applicable

๊ฐœ์ธ ๋ณดํ˜ธ ์žฅ๋น„

Eyeshields, Gloves, type N95 (US)


๊ฐ€์žฅ ์ตœ์‹  ๋ฒ„์ „ ์ค‘ ํ•˜๋‚˜๋ฅผ ์„ ํƒํ•˜์„ธ์š”:

์‹œํ—˜ ์„ฑ์ ์„œ(COA)

Lot/Batch Number

์ ํ•ฉํ•œ ๋ฒ„์ „์„ ์ฐพ์„ ์ˆ˜ ์—†์œผ์‹ ๊ฐ€์š”?

ํŠน์ • ๋ฒ„์ „์ด ํ•„์š”ํ•œ ๊ฒฝ์šฐ ๋กœํŠธ ๋ฒˆํ˜ธ๋‚˜ ๋ฐฐ์น˜ ๋ฒˆํ˜ธ๋กœ ํŠน์ • ์ธ์ฆ์„œ๋ฅผ ์ฐพ์„ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

์ด ์ œํ’ˆ์„ ์ด๋ฏธ ๊ฐ€์ง€๊ณ  ๊ณ„์‹ญ๋‹ˆ๊นŒ?

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ์—์„œ ์ตœ๊ทผ์— ๊ตฌ๋งคํ•œ ์ œํ’ˆ์— ๋Œ€ํ•œ ๋ฌธ์„œ๋ฅผ ์ฐพ์•„๋ณด์„ธ์š”.

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ ๋ฐฉ๋ฌธ

์ด๋ฏธ ์—ด๋žŒํ•œ ๊ณ ๊ฐ

Iain J Abbott et al.
The Journal of antimicrobial chemotherapy, 75(4), 988-996 (2019-12-25)
To assess the antibacterial effects of a single 3โ€‰g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model. An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(3) (2020-01-08)
Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and any benefit of giving multiple
Iain J Abbott et al.
Journal of microbiological methods, 171, 105861-105861 (2020-02-09)
The impact of the bladder environment on fosfomycin activity and treatment response is uncertain. Standard laboratory media does not reflect the biomatrix of urine, where limited nutritional factors are important for growth and antimicrobial kill rates. We compared fosfomycin activity
Pascal Belin et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7426-7431 (2009-05-07)
The gene encoding the cytochrome P450 CYP121 is essential for Mycobacterium tuberculosis. However, the CYP121 catalytic activity remains unknown. Here, we show that the cyclodipeptide cyclo(l-Tyr-l-Tyr) (cYY) binds to CYP121, and is efficiently converted into a single major product in

๋ฌธ์„œ

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

ํ”„๋กœํ† ์ฝœ

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

์งˆ๋ฌธ

1โ€“3 / 3 ์งˆ๋ฌธ ย 
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 ๋‹ต๋ณ€
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers.โ€ฏFor more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 ๋‹ต๋ณ€
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

  3. May I know what is the recommended storage condition for the reconstituted working solution and the estimated shelf life for both the stock and the working solution?

    1 ๋‹ต๋ณ€
    1. Unfortunately, the stability of the material in solution at the working concentration has not been determined. However, similar product 346764, ฮฑ-D-Glucose-6-phosphate monosodium salt, states that aqueous stock solutions are stable for up to 6 weeks at -20ยฐC.

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

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