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Merck
모든 사진(1)

문서

10127647001

Roche

Glucose-6-phosphate

mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

동의어(들):

D-Glucose 6-phosphate disodium salt hydrate, G-6-P-Na2, Robison ester

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About This Item

실험식(Hill 표기법):
C6H11Na2O9P · xH2O
CAS Number:
Molecular Weight:
304.10 (anhydrous basis)
Beilstein:
5199009
MDL number:
UNSPSC 코드:
12352302
PubChem Substance ID:

형태

solid

분자량

(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)

포장

pkg of 5 g

제조업체/상표

Roche

배송 상태

ambient

SMILES string

O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1

InChI key

UUWJZXLTPORJKW-WYFATIGWSA-L

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일반 설명

Disodium salt

애플리케이션

Substrate for glucose-6-phosphatase.

생화학적/생리학적 작용

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.

성분

77% glucose-6-P (enzymatic), 13% sodium, 8% water

품질

Contaminants: <0.2% glucose (enzymatic)

조제법 변형

C6H11O9PNa2

기타 정보

For life science research only. Not for use in diagnostic procedures.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

THE ROLE OF GLUCOSE 6-PHOSPHATE IN THE REGULATION OF GLUCOSE METABOLISM IN HUMAN ERYTHROCYTES.
I A ROSE et al.
The Journal of biological chemistry, 239, 12-17 (1964-01-01)
C Villar-Palasí et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 11(7), 544-558 (1997-06-01)
Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main factor in control of the synthesis of glycogen; insulin has only a potentiating

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