G3126

L-Glutamine

≥99% (HPLC), ReagentPlus^®

• 동의어(들): (S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide
• Linear Formula: H₂NCOCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 56-85-9
• Molecular Weight: 146.14
• Beilstein: 1723797
• EC Number: 200-292-1
• MDL number: MFCD00008044
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24277983
• NACRES: NA.26

속성

• 제품명: L-Glutamine, ReagentPlus^®, ≥99% (HPLC)
• Quality Level: 200
• 제품 라인: ReagentPlus^®
• 분석: ≥99% (HPLC)
• 양식: powder
• 불순물: ≤0.2% free ammonia.; ~0.5% Glutamic acid
• 색상: white to off-white
• mp: 185 °C (dec.) (lit.)
• solubility: 1 M HCl: 50 mg/mL, clear to slightly hazy, colorless
• 양이온 미량물: <0.2% (Ammonia (NH3))
• 응용 분야: cell analysis; peptide synthesis
• 작용기: amide
• 저장 온도: room temp
• SMILES string: N[C@@H](CCC(N)=O)C(O)=O
• InChI: 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
• InChI key: ZDXPYRJPNDTMRX-VKHMYHEASA-N
• 유전자 정보: rat ... Ggt1(116568)

설명

일반 설명

L-Glutamine is a versatile amino acid that plays an essential role in various metabolic processes within the human body. This non-essential amino acid is naturally abundant and contributes significantly to several vital functions. One of its primary functions is acting as the primary carrier of nitrogen in the body. It serves as the transport vehicle for nitrogen, which is a fundamental building block for many biological processes. Additionally, L-Glutamine is a major energy source for numerous types of cells, ensuring they have the energy they need to function optimally.

Moreover, L-Glutamine is essential for maintaining a delicate balance of ammonia in the body. This balance is crucial for preventing toxic ammonia levels. This amino acid facilitates the conversion of glutamic acid to glutamine, a process central to ammonia regulation. L-Glutamine is not only involved in nitrogen transport and energy production but also serves as a key player in various metabolic pathways. It participates in the biosynthesis of proteins, similar to other amino acids. Furthermore, it plays a significant role in the synthesis of urea and purines, vital components for nucleic acid production. L-Glutamine is also a vital resource for generating cellular energy, working closely with glucose for this purpose.

Another essential function of L-Glutamine is its contribution to nitrogen donation for multiple anabolic processes. These processes are vital for building crucial molecules, including purines, which are crucial for DNA production. This amino acid also provides carbon, replenishing the citric acid cycle, a central process in energy production within cells. L-Glutamine is a critical amino acid, acting as a nitrogen carrier, energy source, and contributing to protein synthesis and ammonia regulation. Its versatile functions make it a molecule of significant interest in the fields of cell biology, biochemical research, and metabolomics investigations.

애플리케이션

L-Glutamine has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.[1]It has also been used to study non-enzymatic gluconeogenesis.[2]

생화학적/생리학적 작용

L-glutamine is the most abundant amino acid in the body. It is essential for the synthesis of L-asparagine.[3][4] L-glutamic acid aids the incorporation of NH4⁺ into biomolecules.[5]

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

특징 및 장점

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

기타 정보

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법적 정보

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)