G1251

L-Glutamic acid

≥99% (HPLC), suitable for microbiological culture, ReagentPlus^®

• 동의어(들): (S)-2-Aminopentanedioic acid, Glu
• Linear Formula: HO₂CCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 56-86-0
• Molecular Weight: 147.13
• Beilstein: 1723801
• EC Number: 200-293-7
• MDL number: MFCD00002634
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895052
• NACRES: NA.26

속성

• 제품명: L-Glutamic acid, ReagentPlus^®, ≥99% (HPLC)
• Agency: suitable for SM 5210
• Quality Level: 200
• 제품 라인: ReagentPlus^®
• 분석: ≥99% (HPLC)
• 양식: powder
• 기술: microbiological culture: suitable
• 색상: white to off-white
• mp: 205 °C (dec.) (lit.)
• solubility: 1 M HCl: soluble 100 mg/mL
• density: 1.54 g/cm³ at 20 °C
• 양이온 미량물: C: 40.4-41.2%; N: 9.2-9.8%
• SMILES string: N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
• InChI key: WHUUTDBJXJRKMK-VKHMYHEASA-N
• 유전자 정보: human ... CCR2(1231) , GRIA1(2890) , GRIA2(2891) , GRIA4(2893) , GRIK2(2898) , GRIK3(2899) , GRIK5(2901) , GRIN2B(2904) , GRM2(2912) , SLC1A1(6505) , SLC1A2(6506) ; rat ... Gria1(50592) , Grik1(29559) , Grik2(54257) , Grik4(24406) , Grin2a(24409) , Grm1(24414) , Grm2(24415) , Grm3(24416) , Grm4(24417) , Grm5(24418) , Grm6(24419) , Grm7(81672) , Slc1a2(29482)

설명

애플리케이션

L-Glutamic acid has been used to enhance endogenous acetylcholine overflow.[1] It has been used as a supplement in the growth medium of meat-Spoiling Pseudomonas fragi 72. [2]

생화학적/생리학적 작용

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Glutamic acid, or glutamate, the salt form of glutamic acid, functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as γ-aminobutyric acid.[3] Glutamic acid also plays a key role in many metabolic pathways, that controls growth, reproduction, maintenance and immunity.[4] It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle, and a precursor for the biosynthesis of nucleic acids and certain amino acids.[5][4] In cells, glutamine is converted to glutamate by the enzyme glutaminase.[5]
Glutamine serves as a source of energy for rapidly dividing cells comprising lymphocytes, enterocytes, macrophages and tumors. Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signaling. It is also known to be associated with the inhibition of apoptosis.[4]

법적 정보

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)