D0184

2′-Deoxyuridine 5′-triphosphate sodium salt solution

100 mM in H₂O

• 동의어(들): dUTP sodium salt
• 실험식(Hill 표기법): C₉H₁₅N₂O₁₄P₃ · xNa⁺
• CAS Number: 94736-09-1
• Molecular Weight: 468.14 (free acid basis)
• MDL number: MFCD01630759
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24893218
• NACRES: NA.52

속성

• 분석: ≥99%
• 양식: liquid
• 농도: 100 mM in H₂O
• 색상: colorless
• 외래 활성: DNase, RNase, none detected
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
• InChI key: FVFWWPFKJNTHIQ-UHFFFAOYSA-N

설명

일반 설명

2′-Deoxyuridine 5′-triphosphate (dUTP) is incorporated into DNA during DNA synthesis. It is one of the main intermediate during pyrimidine nucleotide biosynthesis. It is one of the sources of uracil in DNA. Deoxyuridine 5′-triphosphate nucleotidohydrolase suppresses the incorporation of dUTP into DNA. It converts dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP).[1][2]

애플리케이션

2′-Deoxyuridine 5′-triphosphate sodium salt solution has been used in the mouse genomic DNA amplification by polymerase chain reaction (PCR).[3] It is also suitable for conjunction with uracil DNA glycosylase to prevent carryover contamination in PCR. The dUTP is substituted for dTTP in the PCR reaction.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable