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Merck
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주요 문서

PHR1258

Supelco

Chloroquine phosphate

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Chloroquine diphosphate salt, N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt

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크기 선택

1 G
₩165,039

₩165,039


예상 입고일2025년 2월 03일세부사항


벌크 견적 요청

크기 선택

보기 변경
1 G
₩165,039

About This Item

실험식(Hill 표기법):
C18H26ClN3 · 2H3PO4
CAS Number:
Molecular Weight:
515.86
Beilstein:
4223142
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

₩165,039


예상 입고일2025년 2월 03일세부사항


벌크 견적 요청

생물학적 소스

synthetic

Quality Level

Grade

certified reference material
pharmaceutical secondary standard

Agency

BP
EP
USP
traceable to USP 1118000

vapor pressure

<0.0000001 kPa ( 25 °C)

API family

chloroquine

CofA

current certificate can be downloaded

포장

pkg of 1 g

저장 조건

protect from light

기술

HPLC: suitable
gas chromatography (GC): suitable

색상

white to yellow

pH

3.5-4.5 (10% in aqueous solution, pH <6.0)

mp

200 °C (dec.) (lit.)

solubility

water: 50 g/L
benzene: practically insoluble
chloroform: practically insoluble
ethanol: practically insoluble
ether: practically insoluble

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)

InChI key

QKICWELGRMTQCR-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Chloroquine phosphate is a phosphate salt of chloroquine. It belongs to the class of aminoquinoline drugs utilized as antimalarials and amebicides.[1]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

Chloroquine phosphate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin-layer chromatography (TLC) and liquid chromatography (LC).[2][3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAB3715 in the slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Rapid spectrofluorimetric determination of chloroquine phosphate tablets
Nelson O, et al.
International Journal of Drug Development and Research, 2(2), 412-417 (2010)
Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine
Sahraei Z, et al.
International Journal of Antimicrobial Agents, 105945(10.1016) (2020)
Determination of chloroquine and its decomposition products in various brands of different dosage forms by liquid chromatography
Abdelrahman AN, et al.
Journal of Pharmaceutical and Biomedical Analysis, 12(2), 205-208 (1994)
David Tordrup et al.
Malaria journal, 10, 15-15 (2011-01-25)
Recent data have found that Plasmodium ovale can be separated in two distinct species: classic and variant P. ovale based on multilocus typing of different genes. This study presents a P. ovale isolate from a patient infected in Ghana together
Kazuhito Sasaki et al.
Anti-cancer drugs, 23(7), 675-682 (2012-05-09)
Autophagy is a complex of adaptive cellular response that enhances cancer cell survival in the face of cellular stresses such as chemotherapy. Recently, chloroquine diphosphate (CQ), a widely used antimalarial drug, has been studied as a potential inhibitor of autophagy.

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