1.16881

Fractogel^® EMD TMAE (M)

• 동의어(들): Biochromatography, Fractogel^® Ion exchangers, Ion exchanger for LC (Fractogel^® TSK/EMD), Fractogel^® EMD TMAE (M)
• UNSPSC 코드: 41115711

속성

• ligand: (Trimethylammoniumethyl)
• Quality Level: 400
• 설명: strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)
• 무균: sterile (Caustic Stable)
• 제품 라인: Fractogel^®
• 형태: resin
• 파라미터: 240 cm/hr flow rate; 8 bar max. pressure
• 기질 활성군: methacrylate
• 평균 입자 크기: 40-90 μm
• 용량: 100 mg binding capacity (BSA/mg of resin)
• 전이 온도: flash point 35 °C (calculated)
• density: 1.430 g/cm³ at 20 °C
• 벌크 밀도: 1000 kg/m³
• 응용 분야: gene therapy; mAb; recombinant protein
• 분리 기술: anion exchange; strong anion exchange
• 저장 온도: no temp limit

설명

일반 설명

Strong anion exchange Fractogel^® resin featuring the tentacle technology with a trimethylammoniumethyl functional group, for purification of acidic and neutral proteins and peptides from multiple sources, DNA and virus removal, plasmid isolation, vaccine purification, and more

특징 및 장점

Fractogel^® EMD TMAE (M) enables:

• High protein loading conditions resulting in good selectivity and resolution with the tentacle technology
• Excellent binding to large viruses at increased loading
• Homogenous binding with high selectivity and purity
• Reduce operating costs and resin replacement with enduring durability - allowing for multiple cycles of column regeneration and sanitization
• Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

포장

• 1.16881.0100: Fractogel^® EMD TMAE (M) Resin 100ml
• 1.16881.0010: Fractogel^® EMD TMAE (M) Resin 10ml
• 1.16881.0500: Fractogel^® EMD TMAE (M) Resin 500ml
• 1.16881.0050: Fractogel^® EMD TMAE (M) Resin 50ml

Plastic bottle

분석 메모

Appearance: Milky turbid suspension, free from impurities (foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.03 %
Cerium: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.25
Functional test: Separation of conalbumin and human serum albumin

법적 정보

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02
• 신호어: Warning
• 유해 및 위험 성명서: H226
• 예방조치 성명서: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 95.0 °F
• Flash Point (°C): 35 °C