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810611P

Avanti

CNO

Avanti Research™ - A Croda Brand

동의어(들):

25-doxyl-cholesterol

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크기 선택

1 MG
₩1,089,197

₩1,089,197

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모든 사진(2)

크기 선택

보기 변경
1 MG
₩1,089,197

About This Item

실험식(Hill 표기법):
C30H50NO3
CAS Number:
109024-15-9
Molecular Weight:
472.72
UNSPSC 코드:
12352211
NACRES:
NA.25

₩1,089,197

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

양식

powder

구성

(contains 10-15% of the ring-opened ketone, TLC)

포장

pkg of 1 × 1 mg (810611P-1mg)

제조업체/상표

Avanti Research™ - A Croda Brand

지질 유형

ESR probes
ESR probes

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](CC[C@]1([C@](CC=C2C[C@H](CC[C@]32C)O)4[H])[H])([C@]1(CC[C@@]43[H])C)[C@H](C)CCCC5(OCC(C)(C)N5[O])C

InChI

1S/C30H50NO3/c1-20(8-7-15-30(6)31(33)27(2,3)19-34-30)24-11-12-25-23-10-9-21-18-22(32)13-16-28(21,4)26(23)14-17-29(24,25)5/h9,20,22-26,32H,7-8,10-19H2,1-6H3/t20-,22+,23?,24-,25?,26?,28+,29-,30?/m1/s1

InChI key

VPKXVMQRURBFJA-AQHLAHBHSA-N

일반 설명

A new paramagnetic analogue of cholesterol as a tool for studying molecular interactions of genuine cholesterol.

애플리케이션

CNO (25-doxyl-cholesterol) has been used in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes reconstituted with mammalian translocator protein (mTSPO) (mTSPO:DMPC molar ratio of 1:20) for nuclear magnetic resonance (NMR) experiments.[1]
CNO has been used to study the interactions of membrane proteins with cholesterol.[2]

생화학적/생리학적 작용

CNO (25-doxyl-cholesterol) is an analog for native cholesterol. It is used in the preparation of multilamellar vesicles.[3] It is used as a spin-labelled analog of cholesterol.[4]

포장

5 mL Amber Glass Screw Cap Vial (810611P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Insights into cholesterol/membrane protein interactions using paramagnetic solid-state NMR
Jaipuria G, et al.
Chemistry (Weinheim An Der Bergstrasse, Germany), 24(66), 17606-17611 (2018)
Insights into Cholesterol/Membrane Protein Interactions Using Paramagnetic Solid-State NMR
Jaipuria G, et al.
Chemistry?A European Journal , 24(66), 17606-17611 (2018)
L Maurin et al.
Biochimica et biophysica acta, 900(2), 239-248 (1987-06-30)
The synthesis of a new paramagnetic (nitroxide) analogue of cholesterol is described. This compound (called CNO) contains a doxyl group in the lateral chain at position 25. Our results show that CNO retains three molecular interactions which characterize authentic cholesterol:
Characterization of the ternary mixture of sphingomyelin, POPC, and cholesterol: support for an inhomogeneous lipid distribution at high temperatures
Bunge A, et al.
Biophysical Journal, 94(7), 2680-2690 (2008)
Influence of the bovine seminal plasma protein PDC-109 on cholesterol in the presence of phospholipids
Muller P, et al.
European Biophysics Journal, 31(6), 438-447 (2002)

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