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주요 문서

810219P

Avanti

C12-NBD Sphingomyelin

Avanti Research™ - A Croda Brand 810219P, powder

동의어(들):

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphingosine-1-phosphocholine

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크기 선택

1 MG
₩759,017

₩759,017

출고 가능일2025년 4월 15일세부사항

벌크 견적 요청
모든 사진(1)

크기 선택

보기 변경
1 MG
₩759,017

About This Item

실험식(Hill 표기법):
C41H73N6O9P
CAS Number:
254117-01-6
Molecular Weight:
825.03
MDL number:
MFCD02259246
UNSPSC 코드:
12352211
NACRES:
NA.25

₩759,017

출고 가능일2025년 4월 15일세부사항

벌크 견적 요청

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 mg (810219P-1mg)

제조업체/상표

Avanti Research™ - A Croda Brand 810219P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C41H73N6O9P/c1-5-6-7-8-9-10-11-12-13-15-18-21-24-27-38(48)36(34-55-57(52,53)54-33-32-47(2,3)4)43-39(49)28-25-22-19-16-14-17-20-23-26-31-42-35-29-30-37(46(50)51)41-40(35)44-56-45-41/h24,27,29-30,36,38,48H,5-23,25-26,28,31-34H2,1-4H3,(H2-,42,43,45,49,52,

InChI key

FCQMKLRMKNYONQ-YPGNEAGUSA-N

일반 설명

C12-NBD Sphingomyelin is a fluorescent analog of biologically active molecule, sphingomyelin.[1] Sphingomyelin is predominantly found in the animal plasma membrane. It is abundantly present as component of cell membranes in mammals, nematodes, protozoa.[2]

애플리케이션

C12-NBD-sphingomyelin has been used as a substrate to test substrate specificity of neutral ceramidase orthologue encoded by AsahA gene.[3]

생화학적/생리학적 작용

Sphingomyelin (SM) is produced from phosphatidylcholine and ceramide on the cell surface and in lumen of the Golgi. SM′s high packing density and affinity to sterols form a rigid barrier to the extracellular environment. SM is also involved in the formation of lipid rafts in cell membranes, which perform important functions in signal transduction and membrane trafficking.[2]

포장

5 mL Amber Glass Screw Cap Vial (810219P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Sawaki Tada et al.
FEMS microbiology letters, 298(2), 157-165 (2009-08-05)
Ceramide is an important molecule not only structurally but also regulationally as a modulator of various cellular events. Ceramidase (CDase) are classified into three different types (acid, alkaline, and neutral CDases). Neutral CDase could play an important role in the
Characterization of a neutral ceramidase orthologue from Aspergillus oryzae
Tada S, et al.
FEMS Microbiology Letters, 298(2), 157-165 (2009)
Fluorescent and Luminescent Probes for Biological Activity (1999)
Hyun-Seok Lee et al.
International journal of molecular sciences, 21(3) (2020-02-08)
Human epidermis is positioned at the interface with the external environment, protecting our bodies against external challenges, including air pollutants. Emerging evidence suggests that diesel particulate extract (DPE), a major component of air pollution, leads to impairment of diverse cellular
Klazien Huitema et al.
The EMBO journal, 23(1), 33-44 (2003-12-20)
Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product. This reaction is catalysed by SM synthase, an enzyme whose biological potential can

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