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주요 문서

810218P

Avanti

C6-NBD Sphingomyelin

Avanti Research™ - A Croda Brand 810218P, powder

동의어(들):

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sphingosine-1-phosphocholine

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크기 선택

1 MG
₩758,307

₩758,307

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벌크 견적 요청
모든 사진(1)

크기 선택

보기 변경
1 MG
₩758,307

About This Item

실험식(Hill 표기법):
C35H61N6O9P
CAS Number:
94885-04-8
Molecular Weight:
740.87
MDL number:
MFCD01074983
UNSPSC 코드:
12352211
NACRES:
NA.25

₩758,307

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 mg (810218P-1mg)

제조업체/상표

Avanti Research™ - A Croda Brand 810218P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](NC(=O)CCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C35H61N6O9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-21-32(42)30(28-49-51(46,47)48-27-26-41(2,3)4)37-33(43)22-19-17-20-25-36-29-23-24-31(40(44)45)35-34(29)38-50-39-35/h18,21,23-24,30,32,42H,5-17,19-20,22,25-28H2,1-4H3,(H2-,36,37,39,43,46,47)/b21-18+/t30-,32+/m0/s1

InChI key

YDBDYTGWMRUUSN-PERJAUJZSA-N

일반 설명

Sphingomyelin is a membrane phospholipid with a central sphingosine and an amide linked fatty acid. Phosphocholine forms the polar head group.[1] It is one of the major phospholipid present in milk fat globule membrane.[2]

애플리케이션

C6-NBD sphingomyelin is suitable for endocytosis assay.[3]

생화학적/생리학적 작용

Sphingomyelin controls cell growth, differentiation, apoptosis and signal transduction along the membrane. It is known to prevent the proliferation of colon tumour. Sphingomyelin also inhibits cholesterol absorption.[2] Abnormal accumulation of sphingomyelin causes Niemann Pick disease.[1]

포장

5 mL Amber Glass Screw Cap Vial (810218P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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Bioactive Components of Milk, 22-22 (2007)
Apoptosis: Biology and Mechanisms, 66-66 (2013)
mTOR complex 1 activity is required to maintain the canonical endocytic recycling pathway against lysosomal delivery
Dauner K, et al.
The Journal of biological chemistry, 292(14), 5737-5747 (2017)
Mark L Schultz et al.
BMC medicine, 17(1), 200-200 (2019-11-13)
Niemann-Pick disease type C is a fatal and progressive neurodegenerative disorder characterized by the accumulation of unesterified cholesterol in late endosomes and lysosomes. We sought to develop new therapeutics for this disorder by harnessing the body's endogenous cholesterol scavenging particle
Avery L McIntosh et al.
Lipids, 45(6), 465-477 (2010-05-18)
During the last several years, intracellular lipid droplets have become the focus of intense study. No longer an inert bystander, the lipid droplet is now known as a dynamic organelle contributing lipids to many cellular events. However, while the dynamics

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