QBD10867

SPDP-dPEG^®₃₆-NHS ester

>95% (HPLC)

• 동의어(들): OPSS-PEG₁₅₀₀-NHS ester, OPSS-PEG₃₆-NHS ester, SPDP-PEG-NHS ester, SPDP-PEG₃₆-NHS ester
• 실험식(Hill 표기법): C₈₇H₁₆₁N₃O₄₁S₂
• Molecular Weight: 1969.33
• MDL number: MFCD21363283
• UNSPSC 코드: 12352108
• NACRES: NA.22

속성

• 분석: >95% (HPLC)
• 양식: solid or viscous liquid
• 반응 적합성: reaction type: Pegylations
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: S(Sc2ncccc2)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
• InChI key: UABNPFOTLJRLAJ-UHFFFAOYSA-N

설명

특징 및 장점

SPDP-dPEG₃₆-NHS ester is an amphiphilic, water-soluble PEGylation reagent that is designed to crosslink amines and free thiols. SPDP (also referred to as orthopyridyl disulfide, or OPSS) reacts with sulfhydryl groups to form disulfide bonds. The N-hydroxysuccinimidyl (NHS) ester reacts with free amines to form amide bonds. The single molecular weight, discrete chain length polyethylene glycol (dPEG) chain is 115 atoms (137.8 Å) long. SPDP-dPEG36-NHS ester is used like SPDP and its related hydrophobic products. However, the water-soluble dPEG product prevents hydrophobicity-triggered precipitation of compounds to which it is conjugated. SPDP-dPEG₃₆-NHS ester is a monodisperse equivalent of the polymeric PEG₁₅₀₀.

법적 정보

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable