QBD10127

Acid-dPEG^®₁₃-NHS ester

• 동의어(들): Polyethylene glycol
• 실험식(Hill 표기법): C₃₄H₆₁NO₁₉
• Molecular Weight: 787.84
• MDL number: MFCD27952889
• UNSPSC 코드: 12352106
• PubChem Substance ID: 329823881
• NACRES: NA.22

속성

• 분석: >90%
• 양식: solid or viscous liquid
• 반응 적합성: reagent type: cross-linking reagent; reactivity: amine reactive
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)ON1C(CCC1=O)=O
• InChI: 1S/C34H61NO19/c36-31-1-2-32(37)35(31)54-34(40)4-6-42-8-10-44-12-14-46-16-18-48-20-22-50-24-26-52-28-30-53-29-27-51-25-23-49-21-19-47-17-15-45-13-11-43-9-7-41-5-3-33(38)39/h1-30H2,(H,38,39)
• InChI key: IBSDUGROMOGHLR-UHFFFAOYSA-N

설명

특징 및 장점

Acid-dPEG^®₁₃-NHS ester, a unique heterobifunctional dPEG^® crosslinking product, allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG^® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG^® spacers provide precise spacing/distance control, and the dPEG^® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable