900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 동의어(들): Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• 실험식(Hill 표기법): C₁₁H₁₂BrFO₂SSi
• CAS Number: 2088829-15-4
• Molecular Weight: 335.26
• MDL number: MFCD31579818
• UNSPSC 코드: 12352200
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: powder or crystals
• 반응 적합성: reaction type: click chemistry
• 저장 온도: −20°C
• SMILES string: [Si](C)(C)(C)C#Cc1cc(cc(c1)Br)[S](=O)(=O)F
• InChI: 1S/C11H12BrFO2SSi/c1-17(2,3)5-4-9-6-10(12)8-11(7-9)16(13,14)15/h6-8H,1-3H3
• InChI key: CUUVPHAGWQDSCZ-UHFFFAOYSA-N

설명

애플리케이션

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable