Synthesis and solid-state structural characterization of five bile acid amides of 4-aminopyridine (4-AP) are reported. Systematic crystallization experiments revealed a number of structural modifications and/or solvate/hydrate systems for these conjugates. Particularly, cholic acid conjugate exhibited five distinct structure modifications, including
The journal of physical chemistry. A, 115(23), 5785-5793 (2011-01-26)
The adsorption, thermal evolution, and electron irradiation of 2-butanol on Pt(111) were investigated with reflection absorption infrared spectroscopy (RAIRS). A simulated vibrational spectrum of a single 2-butanol molecule was calculated using density functional theory to facilitate vibrational assignments. Exposures of
This article introduces the concept of chiral ion mobility spectrometry (CIMS) and presents examples demonstrating the gas-phase separation of enantiomers of a wide range of racemates including pharmaceuticals, amino acids, and carbohydrates. CIMS is similar to traditional ion mobility spectrometry
Magnetic resonance in chemistry : MRC, 44(2), 132-138 (2005-12-17)
D-Glucose, D-mannose and L-rhamnose were reacted with a racemic mixture of 2-butanol, and the resulting alpha-glycosides were analyzed by 1H NMR with COSY and NOESY experiments. Conformational analysis of alpha-glycosidic bonds performed with molecular modeling and appropriate heteronuclear long-range coupling
Journal of chromatographic science, 48(4), 289-293 (2010-04-24)
A simple, rapid, and reliable method to detect residual levels of tert-butanol in liposomes using sec-butanol as an internal standard has been developed. Solid-phase microextraction (SPME) followed by gas chromatographic analysis was used to quantify the amount of residual tert-butanol