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Merck

Anticonvulsant hypersensitivity syndrome (AHS): a case report.

Tennessee medicine : journal of the Tennessee Medical Association (2013-04-27)
Bradley R Keel, Catherine L Payne
要旨

Anticonvulsant Hypersensitivity Syndrome (AHS) is a rare complication of common drugs used today. It is unusual in that it occurs later than most other drug reactions, about two to six weeks after initiation of the offending agent. It also has a hereditary background unlike most other drug reactions. This reaction is caused by the aromatic amines and causes hepatitis, skin rash, fever, and other systemic organ involvement can occur. The reaction is rare but often fatal, thus the observer should be acutely aware of this in the months following initiation of the agents.

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製品番号
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製品内容

Sigma-Aldrich
5,5-ジフェニルヒダントイン, ≥98%
Supelco
フェニトイン, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
フェニトイン 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
フェニトイン, European Pharmacopoeia (EP) Reference Standard
システム適合性用フェニトイン, European Pharmacopoeia (EP) Reference Standard