1302101

グアンファシン 塩酸塩

United States Pharmacopeia (USP) Reference Standard

• 別名: N (アミノイミノメチル)-2,6-ジクロロベンゼンアセトアミド
• 実験式（ヒル表記法）: C₉H₉Cl₂N₃O · HCl
• CAS番号: 29110-48-3
• 分子量: 282.55
• MDL番号: MFCD00798230
• UNSPSCコード: 41116107
• PubChem Substance ID: 329749977
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: guanfacine
• メーカー／製品名: USP
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• SMILES記法: Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl
• InChI: 1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
• InChI Key: DGFYECXYGUIODH-UHFFFAOYSA-N
• 遺伝子情報: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

詳細

詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

• Reduction of Anxiety-related Reactivity in Primates: Guanfacine hydrochloride mediates anxiety-related reactivity and reduces associated agonistic behavior in two pigtail macaques, showcasing its potential for managing stress and aggression in clinical and veterinary settings (Hopper et al., 2024).


• Enhanced Analgesia for Surgical Procedures: The synergistic interaction of guanfacine with lidocaine enhances cutaneous analgesia, indicating its utility in improving pain management strategies, particularly in surgical environments (Chou et al., 2024).

生物化学的／生理学的作用

α-2ノルアドレナリン受容体アゴニスト。

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

その他情報

Sales restrictions may apply.

安全性情報

• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable