コンテンツへスキップ
Merck

PHR1751

Supelco

グアンファシン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

N (アミノイミノメチル)-2,6-ジクロロベンゼンアセトアミド

ログイン組織・契約価格を表示する


About This Item

実験式(ヒル表記法):
C9H9Cl2N3O · HCl
CAS番号:
分子量:
282.55
EC Number:
MDL番号:
UNSPSCコード:
41116107
PubChem Substance ID:
NACRES:
NA.24

グレード

certified reference material
pharmaceutical secondary standard

品質水準

認証

traceable to USP 1302101

APIファミリー

guanfacine

CofA

current certificate can be downloaded

包装

pkg of 500 mg

テクニック

HPLC: suitable
gas chromatography (GC): suitable

アプリケーション

pharmaceutical (small molecule)

フォーマット

neat

保管温度

2-30°C

SMILES記法

Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl

InChI

1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

InChI Key

DGFYECXYGUIODH-UHFFFAOYSA-N

遺伝子情報

類似した製品をお探しですか? 訪問 製品比較ガイド

詳細

Guanfacine hydrochloride, is a selective α-adrenergic receptor agonist, that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and hypertension.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Guanfacine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by spectrophotometry and high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的/生理学的作用

α-2ノルアドレナリン受容体アゴニスト。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC3708 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


Choose from one of the most recent versions:

試験成績書(COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Guanfacine hydrochloride
USP42/NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 45(3), 2133-2133 (2018)
Spectrophotometric analysis of some guanidino drugs by acid-dye and charge-transfer complexation methods
Wahbi AM, et al.
Journal of Pharmaceutical and Biomedical Analysis, 11(8), 639- 645 (1993)
Guanfacine and secondary mania in children
Horrigan JP and Barnhill LJ
Journal of Affective Disorders, 54(3), 309- 314 (1999)
L A Cornish
Clinical pharmacy, 7(3), 187-197 (1988-03-01)
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage of guanfacine hydrochloride are reviewed. Guanfacine lowers blood pressure by activating CNS alpha adrenoreceptors, which results in sympathetic outflow leading to reduced vascular tone. However, initial hypotensive response to guanfacine may

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)