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59356-U

Supelco

Discovery® Cyano (5 µm) HPLC Columns

Discovery® Cyano HPLC Column

L × I.D. 15 cm × 4.6 mm, HPLC Column

別名:

シアノ結合相カラム

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1 EA
¥107,000

¥107,000


出荷可能日2025年4月22日詳細



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1 EA
¥107,000

About This Item

UNSPSCコード:
41115700
eCl@ss:
32110501
NACRES:
SB.52

¥107,000


出荷可能日2025年4月22日詳細


製品名

Discovery®Cyano HPLCカラム, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

物質

stainless steel column

品質水準

認証

suitable for USP L10

製品種目

Discovery®

特徴

endcapped

メーカー/製品名

Discovery®

包装

1 ea of

標識化の程度

4.5% Carbon loading

パラメーター

≤70 °C temp. range
400 bar pressure (5801 psi)

テクニック

HPLC: suitable
LC/MS: suitable

L × 内径

15 cm × 4.6 mm

表面積

200 m2/g

表面被覆率

3.5 μmol/m2

不純物

<10 ppm metals

Matrix

silica gel, high purity, spherical base material
fully porous particle

マトリックス活性基

cyano phase

粒径

5 μm

ポアサイズ

180 Å

動作pH範囲

2-8

アプリケーション

food and beverages

分離法

hydrophilic interaction (HILIC)
normal phase
reversed phase

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詳細

Discovery®シアノHPLC検出カラムは、第4級アンモニウム塩を含む強塩基性の測定物質の保持および分離に使用され、優れたピーク形状を誇ります。

特徴および利点

  • 疎水性分析対象物の迅速な溶出に要する疎水性の低さ
  • 優れたピ-ク形状および強塩基性分析対象物の保持
  • 極性分析対象物の保持
  • 独自の選択性
  • C18カラムよりも顕著に低い保持(低濃度の有機系移動相が必要)
  • 安定で低ブリ-ドのLC-MS分離
  • 水系有機溶媒の濃度が高い移動相で使用可能

法的情報

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

13 - Non Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

59356-U:


最新バージョンのいずれかを選択してください:

試験成績書(COA)

Lot/Batch Number

適切なバージョンが見つかりませんか。

特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
K Umekawa et al.
Japanese journal of pharmacology, 84(1), 7-15 (2000-10-24)
We describe the pharmacological characteristics of SM-19712 (4-chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl] benzenesulfonamide, monosodium salt). SM-19712 inhibited endothelin converting enzyme (ECE) solubilized from rat lung microsomes with an IC50 value of 42 nM and, at 10 - 100 microM, had no effect on other
Christophe Morisseau et al.
Analytical biochemistry, 414(1), 154-162 (2011-03-05)
The microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of numerous xenobiotics. In addition, it has a potential role in sexual development and bile acid transport, and it is associated with a number of diseases such as
Srdan Verstovsek et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(3), 788-796 (2008-02-05)
The discovery of an activating somatic mutation in codon 617 of the gene encoding the Janus kinase (JAK)-2 (JAK2 V617F) in patients with myeloproliferative disorders has opened new avenues for the development of targeted therapies for these malignancies. However, no
Ye Ding et al.
Chemical communications (Cambridge, England), 47(33), 9495-9497 (2011-07-19)
A novel and facile DDQ-mediated dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones is described. The formation of lactones proceeds by a radical ion mechanism, which has been established by DPPH˙-mediated chemical identification, ESR spectroscopy

質問

1–4/4 質問  
  1. ¿Me podrías confirmar que la composición de esta columna es end-capped cyanosilyl silica gel for chromatography R? Gracias!

    1 回答
    1. These columns are end-capped, but the phase is cyanopropyl.

      役に立ちましたか?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      役に立ちましたか?

  3. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      役に立ちましたか?

  4. Please provide the below details for the column Carbon loading%- Pore size- Surface area- pH stability- End capping-

    1 回答
    1. TS Answer:
      - 4.5% Carbon loading
      - Pore size: 180 Å
      - Surface area: 200 m2/g
      - Operating pH range: 2-8
      - Endcapped
      - Particle Size: 5 μm
      - Temperature Range: ≤70 °C
      - Maximum Pressure: 400 bar pressure (5801 psi)
      - Suitable for USP L10

      役に立ちましたか?

レビュー

アクティブなフィルタ

  1. India
    • 1件のレビュー
    • 0件の投票
    星2/5個です。

    Column to column variation

    Variation in Retention time from column to column observed

    Googleで翻訳する

    役に立ちましたか?

    1. Sigma-Aldrich Corporationからの回答:

      Thank you for your review. While minor variability between batches may occur, the degree of difference in retention times would be impacted by run times. Assuming all other conditions are identical, an overall +/- 5% may be possible. As there are a number of variables to consider, we encourage customers who experience problems with our products to call or email us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.

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